An experiment was conducted to study the effects of carbon tetrachloride (CCl4) on post-peak performance and serum enzymes of Hy-Line W-36 laying hens from 32-36 weeks of age. The experiment was carried out with a total of 192 laying hens in a completely randomized block design. During the experiment laying hens were allocated to 4 groups consisted of T1) no CCl4 as control diet, T2, T3 and T4)...

In order to investigate the effects of peppermint (Mentha piperita L.) alcoholic extract on liver injury caused by the oxidant carbon tetrachloride (CCl4), an experiment was performed as a completely randomized design in a factorial arrangement (2 × 2) with 4 replications of 10 broilers each. Factors included two levels of peppermint leaf alcoholic extract (0 and 2 mL/Kg body weight) and CCl4 (...

BACKGROUND Ginsenosides, the major bioactive compounds in ginseng root, have been found to have antioxidant, immunomodulatory and anti-inflammatory activities. This study investigated the effects of ginsenosides on carbon tetrachloride (CCl4)-induced hepatitis and liver fibrosis in rats. METHODS Male Sprague-Dawley rats were randomly divided into four groups: control, CCl4, CCl4 + 0.5 g/kg Pa...

BACKGROUND The liver performs diverse functions that are essential for life. In the absence of reliable liver protective drugs, a large number of natural medicinal preparations are used for the treatment of liver diseases. Therefore the present study aims to investigate the hepatoprotective effects of Salix subserrata Willd flower ethanolic extract (SFEE) against carbon tetrachloride (CCl4)-ind...

The effects of different concentrations of the hydroalcoholic extract of dried powdered leaves of Cichorium intybus L., on CCl4-induced hepatotoxicity in vivo in rats and CCl4-induced cytotoxicity in isolated rat hepatocytes were investigated. Rats received different concentrations of the extract by i.p. injection for 3 consecutive days before the injection of (3ml/kg) CCl4 (i.p.). Twenty four ...

This study concerns the modifying effect of carbon tetrachloride (CCl4) on methylazoxymethanol acetate (MAM)-induced intestinal carcinogenesis in ACI rats of both sexes. Forty five animals were given CCl4 (0.5 ml/kg body weight) through a stomach tube, followed by an i.p. injection with MAM (25 mg/kg body weight) 24 hours after CCl4 treatment. The paired administrations were done once a week fo...

an experiment was conducted to study the effects of carbon tetrachloride (ccl4) on post-peak performance and serum enzymes of hy-line w-36 laying hens from 32-36 weeks of age. the experiment was carried out with a total of 192 laying hens in a completely randomized block design. during the experiment laying hens were allocated to 4 groups consisted of t1) no ccl4 as control diet, t2, t3 and t4)...

The purpose of this study was to investigate the protective effect of polysaccharides from Boschniakia rossica against hepatotoxicity induced by carbon tetrachloride (CCl4). Boschniakia rossica polysaccharides was administered intragastrically once daily for 7 days. One hour after the final treatment, mice were treated intraperitoneally with 80 mg/kg of CCl4. CCl4-induced hepatotoxicity was man...

BACKGROUND To find a non-invasive method of diagnosing hepatic fibrosis and cirrhosis, we evaluated the relationship of the hepatic cirrhosis grade between histopathology and mean grey level (MGL) in B-mode ultrasonography in CCl4-induced liver cirrhosis. MATERIALS AND METHODS Three groups of rats were treated with olive oil, CCl4, and CCl4 + silymarin. Rats were sacrificed at weeks 4, 8 and ...

The inflammatory chemokine (C-C motif) ligand 4 (CCL4) plays an important role in the pathogenesis and progression of cancer. In particular, higher serum CCL4 levels in patients with oral squamous cell carcinoma (OSCC) are associated with a more advanced stage of disease. OSCC accounts for approximately 95% of oral cancer in Taiwan and has a poor prognosis, due to aggressive local invasion and ...