BACKGROUND AND PURPOSE Carotid bulb diaphragm (CBD) has been described in young carotid ischemic stroke (CIS) patients, especially in blacks. However, the prevalence of CBD in CIS patients is unknown, and whether CBD is a risk factor for CIS remains unclear. We assessed the association between CBD and incident CIS in a population-based study. METHODS We selected all young (<55 years) CIS pati...

To investigate the effect of repair of bioabsorbable poly(lactide) (PLA) biliary stent in common bile duct (CBD) transection injury in canine prior to the clinical application. Circular tubing CBD stent was prepared by melt extraction technique using PLA. A transection incision was made on CBD of the normal canine, and then closed the incision with laser welding followed the implantation of PLA...

Introduction The recurrence rate of choledocholithiasis after endoscopic stone extraction differs from 6.4% to 24%. Although the etiology of stone recurrence after initial ERCP has not been fully elucidated, some risk factors for stone recurrence have been reported: a common bile duct (CBD) dilatation, periampullary diverticula (PAD), pneumobilia, and acute CBD angulation. The early detection a...

This research attempts to span the gap between the AI in medicine (AIM) and consistency-based diagnosis (CBD) communities by applying CBD to physiology. The highly-regulated nature of physiological systems challenges standard CBD algorithms, which are not tailored for complex dynamic systems. To combat this problem, we separate static from dynamic analysis, so that CBD is performed over the ste...

We have previously reported that cannabidiol (CBD) lowers the incidence of diabetes in young non-obese diabetes-prone (NOD) female mice. In the present study we show that administration of CBD to 11-14 week old female NOD mice, which are either in a latent diabetes stage or with initial symptoms of diabetes, ameliorates the manifestations of the disease. Diabetes was diagnosed in only 32% of th...

Cannabidiol (CBD) is the main non-psychotropic component of the glandular hairs of Cannabis sativa. It displays a plethora of actions including anticonvulsive, sedative, hypnotic, antipsychotic, antiinflammatory and neuroprotective properties. However, it is well established that CBD produces its biological effects without exerting significant intrinsic activity upon cannabinoid receptors. For ...

Sоftware reuse, or component-based development is regarded as one оf thе most important sоftware technologies іn order to reduce lead times, іncrease functionality, and reduce costs. Thе concept оf component-based development (CBD) is widely used іn sоftware (SW) development. CBD facilitates reuse оf thе existіng components with thе new ones. Thе well known architectures оf CBD are ActiveX, com...

Anecdotal and scientific evidence suggests that Cannabis use may be beneficial in inflammatory bowel disease (IBD) patients. Here, we have investigated the effect of a standardized Cannabis sativa extract with high content of cannabidiol (CBD), here named CBD BDS for "CBD botanical drug substance," on mucosal inflammation and hypermotility in mouse models of intestinal inflammation. Colitis was...

Plant-derived cannabinoids (phytocannabinoids) are compounds with emerging therapeutic potential. Early studies suggested that cannabidiol (CBD) has anticonvulsant properties in animal models and reduced seizure frequency in limited human trials. Here, we examine the antiepileptiform and antiseizure potential of CBD using in vitro electrophysiology and an in vivo animal seizure model, respectiv...

A spatial analysis of a large 20th century urban settlement (town/city) easily presents the celebrated central Business District (CBD). Theories of Urban Land Economics have easily justified and attempted to explain the existence of such a district activity area within the cityscape. This work examines the gradual emergence and development of the CBD in Lafia Town, Nigeria over 20 years and the...