نتایج جستجو برای: cataracts
تعداد نتایج: 3603 فیلتر نتایج به سال:
BACKGROUND Atopic dermatitis (AD) is a common skin disorder of increasing prevalence. Many ophthalmologic conditions are associated with AD, including cataract formation. Posterior and anterior subcapsular cataracts have been described in AD. Topical and systemic corticosteroids have been implicated in the development of cataracts. The precise pathogenic mechanisms and risk factors for developm...
PURPOSE Cataracts are often considered to be an unavoidable consequence of aging. Oxidative damage is a major cause or consequence of cortical and nuclear cataracts, the most common types of age-related cataracts. METHODS In this review, we consider the different risk factors, natural history and etiology of each of the 3 major types of age-related cataract, as well as the potential sources o...
PURPOSE Lens epithelial cells transdifferentiate to myofibroblasts during the formation of anterior subcapsular cataracts and secondary cataracts. One of the defining characteristics of myofibroblasts is the expression of alpha-smooth muscle actin (alpha-SMA). This study investigated some of the factors that influence alpha-SMA expression in lens epithelial cells. METHODS Bovine, rabbit, and ...
AIMS To determine the prevalence of and risk factors for cataracts in a rural region of central Myanmar. METHODS A cross-sectional, population-based survey of inhabitants >or=40 years of age from villages of central Myanmar; 2076 participated, and 2044 (82.3%) had an examinable lens in at least one eye. Data recording included smoking history, occupation, education level, betel-nut chewing, h...
BACKGROUND AND OBJECTIVE To assess the results of coaxial phacoemulsification through 1.8-mm coaxial microincision cataract surgery (C-MICS) phacoemulsification with foldable intraocular lens implantation in eyes with hard cataracts in comparison to eyes with soft cataracts. PATIENTS AND METHODS Group 1 consisted of 40 eyes of 40 patients with hard cataracts (grade ≥ 4, Lens Opacities Classif...
PURPOSE We sought to identify the genetic defect in a large, five-generation Chinese family with autosomal dominant progressive polymorphic congenital coronary cataracts and to examine the clinical features in detail. METHODS Clinical and ophthalmologic examinations were conducted on family members. All members were genotyped with microsatellite markers at loci previously associated with cata...
PURPOSE To determine the levels of mRNAs encoding markers of fibrosis in lens epithelial cells (LECs) from patients with anterior polar cataracts and to test whether transforming growth factor (TGF)-beta enhances the expression of mRNAs for mesenchymal markers in LECs. METHODS LECs attached to the anterior capsules of patients with nuclear or anterior polar cataracts were analyzed by reverse ...
Program Number: 2183 Poster Board Number: B0036 Presentation Time: 3:45 PM–5:30 PM Characteristics of Anterior Polar Cataracts in Children Lena Dixit1, Michael Puente1, Kimberly Yen2. 1Ophthalmology, Baylor College of Medicine, Houston, TX; 2Ophthalmology, Texas Children’s Hospital, Houston, TX. Purpose: To evaluate pediatric patients with unilateral or bilateral anterior polar cataracts and as...
Surgically removable cataracts remain the leading cause of blindness worldwide. The disease is much more common in developing countries due to the absence of ophthalmologists who can perform cataract surgery. Though many factors influence cataract development, the vast majority of cases are age-related and develop in persons over 50 years old. Studies show that women are more susceptible to cat...
OBJECTIVE To quantify the prevalence of, and risk factors for, diabetic retinopathy and cataracts in patients with type 2 diabetes, and their spouse controls, enrolled from 5 centers in 2 West African countries (Ghana and Nigeria). METHOD The analysis cohort was made up of 840 subjects with type 2 diabetes, and their 191 unaffected spouse controls, who were enrolled and examined in Lagos, Enu...
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