AIM This study was designed to investigate the bioactive compounds in Costus afer Ker Gawl, an indigenous African medicinal plant whose leaf and stem extracts are used in the treatment of chronic inflammatory diseases, especially rheumatism and arthritis. MATERIALS AND METHODS The bioactive compounds present in the n-butanol fractions of C. afer leaf and stem were identified using qualitative...

Background. Cyclic mastalgia (CM) is premenstrual bilateral and diffuse breast pain that presents cyclically affects women in their reproductive years. It may associate with latent hyperprolactinemia due to the insufficient inhibitory effect of dopamine on pituitary gland. Vitex agnus-castus (VAC) known for its dopaminergic activity possible actions CM hyperprolactinemia. However, treatment VAC...

Vitex agnus-castus L. is a medicinal plant which is used in several dosage forms for women hormonal disorders and standardized according to the iridoids or flavonoids content. Aucubin, an iridoid glycoside, considered as a marker in some formulations. In this research, a thin layer chromatographic method with densitometric detection has been developed for quantitative determination of aucubin i...

Vitex agnus-castus L. is a medicinal plant which is used in several dosage forms for women hormonal disorders and standardized according to the iridoids or flavonoids content. Aucubin, an iridoid glycoside, considered as a marker in some formulations. In this research, a thin layer chromatographic method with densitometric detection has been developed for quantitative determination of aucubin i...

Introduction: PCOS is an important reproductive and endocrine disorder in women in the reproductive age. Present reports indicate that Vitex agnus-castus acts through hypothalamus-pituitary axis. This study was carried out to evaluate the effects of Vitex fruit hydroalcoholic extract on the alteration of sex hormones in a PCOS animal model. Methods: Following 14 days of monitoring of estrous...