AIMS The aim of this study was to examine the circulating levels of vascular endothelial growth factor, following coronary artery bypass graft surgery performed using both standard cardiopulmonary bypass or the 'octopus technique' on the beating heart. BACKGROUND Vascular endothelial growth factor has a number of effects that are beneficial in the setting of coronary artery bypass graft surge...

CONTEXT Conventional coronary artery bypass graft surgery with use of cardiopulmonary bypass (on-pump CABG) is associated with excellent long-term cardiac outcomes but also with a high incidence of cognitive decline. The effect of avoiding cardiopulmonary bypass (off-pump CABG) on long-term cognitive and cardiac outcomes is unknown. OBJECTIVE To compare the effect of off-pump CABG and on-pump...

Hereditary angioedema (HAE) is an autosomal dominantly inherited deficiency of C1-inhibitor, and it is an extremely rare condition. During surgery, oedema can be induced by a variety of stresses, and a high mortality rate has been reported. Since open-heart surgery involves cardiopulmonary bypass, the inflammatory response and complement activity are increased, meaning that an even greater risk...

Currently coronary artery bypass grafting (CABG) is the most commonly used procedure for revascularization of coronary heart disease. However it may not be suitable for the patients with diffuse coronary artery lesions, for which endarterectomy is a way but it’s not feasible to thin coronary artery without inner lumen or to the immature plaque. In this case, it may be a proper therapeutic optio...

BACKGROUND Surgeons have adopted off-pump coronary artery bypass grafting (OPCAB) in an effort to reduce the morbidity of surgical revascularization. However, long-term outcome of OPCAB compared with conventional coronary artery bypass grafting (CABG) remains poorly defined. METHODS AND RESULTS Using logistic regression analysis and proportional hazards modeling, short-term and long-term outc...

OBJECTIVE Age is considered to be the strongest predictive factor of postoperative cognitive dysfunction (POCD) after cardiac surgery. Coronary artery bypass grafting (CABG) without the use of cardiopulmonary bypass is considered to be less harmful to the patient, especially in terms of neurological complications. METHODS The study was a sub-study of the randomized best bypass surgery trial t...

BACKGROUND Robotic-assisted coronary artery bypass graft surgery (CABG) has been performed over the past decade. Despite encouraging results from selected centres, there is a paucity of robust clinical data to establish its clinical safety and efficacy. The present systematic review aimed to identify all relevant clinical data on robotic CABG. The primary endpoint was perioperative mortality, a...

Background: Major leg wound complications after coronary artery bypass graft procedures are infrequent and few are reported in the litrature.We present our experience in treating 30 patients with major leg wound complications after coronary revascularization procedures. Materials and Methods: A retrospective review of 2100 bypass procedures with saphenous veingraft performed over a 5-years p...

Background/Introduction Acute kidney injury (AKI) occurs in up to 30% of patients undergoing coronary artery bypass grafting. Development of kidney injury is associated with high overall mortality and a more complicated hospital course. Cardiopulmonary bypass is considered as one of the major risk factors for developing AKI. Off-pump coronary artery bypass (OPCAB) grafting eliminates the need f...