C linically, mineralocorticoid receptor (MR) antagonists are widely prescribed for the treatment of hyper-tension and heart failure because of their diuretic action in aldosterone-sensitive distal nephron. Clinical trials of MR antagonism in patients with various degrees of heart failure severity have also demonstrated a pronounced reduction of cardiovascular mortality in MR antagonist–treated ...

OBJECTIVE Weight loss among metabolically healthy obese (MHO) individuals may be unnecessary or result in elevated cardio-metabolic risk. We studied the effects of exercise- or diet-induced weight loss on cardio-metabolic risk among MHO and metabolically abnormal obese (MAO) adults. RESEARCH DESIGN AND METHODS Participants were 63 MHO and 43 MAO adults who took part in 3 to 6 months of exerci...

Police work is one of the most stressful occupations in the world due to their enormous stresses, uncertainty in work, lack of support from the superior, etc. They were suffering from different types of physical and mental disorders. But only a few studies were carried out in India. The present study was conducted to evaluate the cardiovascular status of police officers working in different pol...

Ttiis is a useful book, in which the place of cortisone and other steroid drugs in the treatment of the rheumatic diseases is reviewed. The book falls naturally into two parts. The first section conisists of five chapters, and is concerned with the use of cortisone in rheumatoid arthritis. The second section consists of two chapters, the first of which decribes the general use of cortisone in d...

The Cardio-vascular Tissues aimed for clinical use are submitted to the European Regulation (Directives 2004/ 23EC, 2006/17EC and 2006/86EC) to assure high level of tissue quality and security. The European Directive was transposed into the Member state legislation and Standards, specific to their needs and possibilities. The Cardio-vascular tissues are recovered in the operating theatre or ano...

The incidence of syphilitic cardio-vascular disease is small in comparison with heart disease resulting from acute rheumatism and arterio-sclerosis; and of all patients suffering from cardiac disease less than one in twenty is found to be suffering from disease due to syphilis. Autopsies on syphilitic subjects have shown the aorta to be diseased in half the cases examined and recent observation...

OBJECTIVE The current study aimed to investigate the association of wrist circumference with major cardio metabolic risk factors. METHODS This study was conducted in 2005-2007 among 3000 first-degree relatives of diabetic patients in Isfahan, Iran. RESULTS Overall, 1709 (386 males and 1323 females) participants were enrolled in this study. The association of wrist circumference with cardio-...

Dear Sir The International Atherosclerosis Society (IAS) recently released harmonized guidelines for prevention of atheroscle-rotic disease through clinical management. 1 These guidelines integrate and harmonize existing guidelines for this purpose. Thanks to a large number of clinical trials, it is now possible to provide strong evidence-based guidelines for risk factor modification to prevent...

AIM To evaluate progression of arteriosclerosis using cardio-ankle vascular index(CAVI) and carotid duplex ultrasonography(DUS) in young and adolescent patients considered to be at risk of cardiovascular disease. METHODS We evaluated the progression of arteriosclerosis using CAVI and carotid DUS in 240 young and adolescent patients. Dyslipidemia(DL), hypertension(HT), and diabetes mellitus(DM...