نتایج جستجو برای: cardiac troponin
تعداد نتایج: 281281 فیلتر نتایج به سال:
Objective To evaluate how selection of patients for high sensitivity cardiac troponin testing affects the diagnosis of myocardial infarction across different healthcare settings.Design Prospective study of three independent consecutive patient populations presenting to emergency departments.Setting Secondary and tertiary care hospitals in the United Kingdom and United States.Participants High s...
STUDY OBJECTIVE Myocardial contusion may induce life-threatening complications, but its diagnosis is difficult. Circulating cardiac troponin T is considered a highly sensitive and specific marker of myocardial cell injury. We investigate the value of cardiac troponin T measurement in the diagnosis of myocardial contusion. DESIGN Prospective study. SETTING Level 1 trauma center. METHODS We...
The rapid and reliable diagnosis of acute myocardial infarction is a major unmet clinical need. We conducted a multicenter study to examine the diagnostic accuracy of new, sensitive cardiac troponin assays performed on blood samples obtained in the emergency department from 718 consecutive patients who presented with symptoms suggestive of acute myocardial infarction. Cardiac troponin concentra...
The authors present a practical approach for physicians in clinical practice to use cardiac troponins in the interpretation of heart disease and myocardial damage. Laboratory results that fall within the intermediate area of facility-specific cutoff reference values for elevated troponin levels confer lower risks to patients than do higher levels of cardiac troponin. Perhaps not surprisingly, t...
Introduction Perioperative myocardial infarction (PMI) in the setting of cardiac surgery represent a considerable risk to patients with significant mortality and morbidity. The role of highly sensitive cardiac troponin T (hsTnT) has not been evaluated in the setting of cardiac surgery, instead Cardiac Troponin T (TnT) and Creatine Kinase MB (CK-MB) are commonly used for the diagnosis of PMI [1].
OBJECTIVES to determine the incidence of post-operative troponin I rises and its association with 1-year all-cause mortality and cardiac events after emergency orthopaedic-geriatric surgery, which has not been studied before. METHODS one hundred and two patients over the age of 60 were recruited and followed up at 1 year. All consented to serial troponin I measurements peri-operatively. RES...
Discovered by Ebashi, Troponins are regulatory proteins in cardiac muscle that modulate the interaction between actin and myosin, during the calcium-mediated contraction of cardiac muscle. Three distinct tissue specific isoforms of Troponin I have been identified, two in skeletal muscle and one in cardiac muscle. The cardiac isoform of Troponin I (cTnI) has an additional sequence of 31 amino ac...
Introduction: The purpose of this research was to explain the protective effect of quercetin on cardiac fatigue caused by exercise in skyrunning runners. Methods: 26 professional sky running athletes voluntarily and purposefully participated in this race. Random people were placed in 2 groups: quercetin (13 people) and placebo (13 people). The race was held in the central Alborz mountains, the...
The essential role of cardiac troponin in the diagnosis of acute myocardial infarction has led to the development of high-sensitivity assays, which are able to detect very small amounts of myocardial necrosis. The high-sensitivity cardiac troponin T assay, however, is not entirely specific for myocardial injury. This case report describes a 48-year-old woman, who, two years after cardiac transp...
BACKGROUND Levels of cardiac troponin, a sensitive and specific marker of myocardial injury, are often elevated in critically ill patients. OBJECTIVES To document elevated levels of cardiac troponin I in patients in a medical-surgical intensive care unit and the relationship between elevated levels and electrocardiographic findings and mortality. METHODS A total of 198 patients expected to ...
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