We report a rare case of bilateral metachronous bronchial typical carcinoid tumor surgically treated. At the age of 33 years, the patient underwent, in another hospital, a left upper lobectomy for a typical carcinoid tumor. After 4 years, the patient manifested the symptoms of a new central typical carcinoid tumor located at the origin of the middle lobe bronchus and infiltrating the intermediu...

Carcinoid tumors are malignancies originating from neuroendocrine cells, most commonly encountered in the gastrointestinal tract, in a rate of 64%, with the majority affecting the ileum. Certain genetic syndromes sometimes include carcinoid tumors in their phenotype. These malignancies may be rather asymptomatic, although occasionally they behave aggressively. They are typically diagnosed due t...

Carcinoid syndrome (CS), mostly associated with small intestinal neuroendocrine tumors (SI-NETs) or lung-related NETs, is characterized by symptoms related to hormonal secretion and long-term complications, including carcinoid heart disease (CHD), which potentially life-threatening. In the early stages of disease, are non-specific, leads delayed diagnoses. The availability reliable tumor marker...

Carcinoid is a rare tumor originating from neuroendocrine cells, which are generally localized in the gastrointestinal tract. It has an annual incidence of 1.5 persons per 100 000. Usually, only carcinoid tumors that invade the liver result in pathological changes to the heart. The cardiac manifestations are caused by paraneoplastic effects of vasoactive substances such as serotonin, bradykinin...

OBJECTIVES To describe the early and late outcomes of carcinoid patients undergoing surgical heart valve replacement. METHODS In a retrospective study, records of patients with symptomatic carcinoid heart disease referred for valve surgery between 1993 and 2010 at two academic centres were reviewed. The perioperative and postoperative outcomes were analysed. RESULTS Nineteen patients, with ...

INTRODUCTION Endometriosis is occasionally found in the appendix, particularly in severe forms of deep infiltrating disease. Carcinoid tumor is the most common neoplasm of the appendix and may be overlooked or misdiagnosed when there are multiple endometriosis lesions in the pelvis. CASE DESCRIPTION We describe two cases of carcinoid tumor diagnosed in patients who underwent surgery to treat ...

In this issue 1-5 Bronchial carcinoid Tumors: diagnosis and managemenT 5 conTinuing medical educaTion evenTs 6-8 selecTions from The Peer-reviewed liTeraTure 9 lung cancer meeTings and symPosia Carcinoid tumors are rare neuroendocrine tumors that arise from enterochromaffin cells found throughout the gastrointestinal and bronchopulmonary systems. Carcinoids are predominantly found in the gastro...

NUMEROUS reports of cases of malignant carcinoid associated with acquired cardiovascular abnormalities have appeared in the medical literature since this syndrome was first recognized as a clinical entity. Despite the fact that the intracardiac abnormalities characteristic of this interesting disease are almost exclusively confined to the right side of the heart, catheterization studies have on...

Abstract Background Carcinoid heart disease is an uncommon manifestation of carcinoid syndrome that can present to a cardiac surgeon as complex constellation structural problems. Patients develop progressive valve disease, more commonly the right-sided valves but sometimes involving left, which will in turn impact function. Without intervention, portends dismal prognosis. Given rarity with thes...

We report the case of a 62-year-old woman in whom carcinoid disease had been diagnosed 6 years earlier. She subsequently developed tricuspid and pulmonary valve disease. Both valves were incompetent and mildly stenotic. The tricuspid valve required surgery; the pulmonary vaive was explored but not treated. Valve surgery in patients with carcinoid disease is discussed in light of the prognosis o...