نتایج جستجو برای: carbamylation

تعداد نتایج: 238  

Journal: :Molecules 2017
Ying Fu Jing-Yi Wang Dong Zhang Yu-Feng Chen Shuang Gao Li-Xia Zhao Fei Ye

A series of novel sulfonylurea benzothiazolines was designed by splicing active groups and bioisosterism. A solvent-free synthetic route was developed for the sulfonylurea benzothiazoline derivatives via the cyclization and carbamylation. All compounds were characterized by IR, ¹H-NMR, 13C-NMR, HRMS. The biological activity tests indicated the compounds could protect maize against the injury ca...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2011
Jiayue Cui Jason Hao Olesya A Ulanovskaya Joseph Dundas Jie Liang Sergey A Kozmin

We have developed an efficient strategy to a skeletally diverse chemical library, which entailed a sequence of enyne cycloisomerization, [4 + 2] cycloaddition, alkene dihydroxylation, and diol carbamylation. Using this approach, only 16 readily available building blocks were needed to produce a representative 191-member library, which displayed broad distribution of molecular shapes and excelle...

2014
Ling-Xing Shan Ping-Hua Sun Bao-Qin Guo Xing-Jun Xu Zhi-Qiang Li Jia-Zhi Sun Shu-Feng Zhou Wei-Min Chen

Seventeen acylides bearing an aryl-tetrazolyl alkyl-substituted side chain were synthesized, starting from clarithromycin, via several reactions including hydrolysis, acetylating, esterification, carbamylation, and Michael addition. The structures of all new compounds were confirmed by (1)H nuclear magnetic resonance spectroscopy, (13)C nuclear magnetic resonance spectroscopy, and mass spectrom...

2009
Michael Holzer Martin Gauster Ruth Birner-Grünberger Gunther Marsche

Background Increasing interest has focused on the relative functionality of high-density lipoprotein (HDL), highlighted by observations that cardiovascular events can occur even in the presence of high levels of HDL cholesterol. Myeloperoxidase (MPO), a heme protein abundant in leucocytes, colocalizes with HDL in the human artery wall and has emerged as a potential participant in multiple phase...

Journal: :Clinical Journal of the American Society of Nephrology 2013

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