Canine mammary carcinoma is a highly metastatic tumor that is poorly responsive to available treatment. Therefore, there is an urgent need to identify novel agents for therapy of this disease. Recently, we reported that the oncolytic vaccinia virus GLV-1h68 could be a useful tool for therapy of canine mammary adenoma in vivo. In this study we analyzed the therapeutic effect of GLV-1h68 against ...

Canine parvovirus type 2 (CPV-2) is the main etiological agent of viral enteritis in dogs. Actually in literature, CPV-2 has been reported with clinical signs that vary from the classical disease, and immunochromatography test and PCR technique have been introduced to veterinary hospitals to confirm CPV-2 diagnosis and other infections. However, the reliability of these techniques has been poor...

Introduction The etiologic agent of canine monocytic ehrlichiosis (CME), the rickettsia Ehrlichia canis (E. canis), is a small pleomorphic gram-negative coccoid bacteria that parasitizes circulating monocytes intracytoplasmically in clusters of organisms called morulae. The disease is also known as canine rickettsiosis, canine hemorrhagic fever, tracker dog disease, canine tick typhus, Nairobi ...

We have generated GFP expressing recombinant Newcastle Disease Virus (rNDV-GFP) based on a live vaccine strain which contains a less pathogenic cleavage site of F protein leading to restricted viral growth in vivo. We evaluated the rNDV have an effect of oncolytic activity to B16 melanoma cell. The rNDV-GFP infected efficiency to B16 cells and induced cell death. Apoptosis-related genes, Bax an...

heartworm infection is one of the most important parasitic diseases in dogs and an increasing number of cases are reported each year by necropsy in ahvaz. this study was conducted to determine the prevalence of dirofilaria immitisinfection and to investigate the risk factors related to heartworm disease in urban dogs in this area. blood samples were collected from 100 dogs from feb 2007 to feb ...

Bilateral empyema associated to infectious pericarditis is an extremely rare, yet life-threatening condition. Pleuroscopy-medical thoracoscopy has proved its efficacy in series of patients with empyema. Yet, all reported cases treated by this technique, concerned patients with pleural infection located to a single hemithorax. We present the case of a 71-year-old man with bilateral empyema treat...

In July 2016 we described the first known case of canine ocular thelaziosis in the UK in a dog recently imported from Romania. Here we confirm our initial diagnosis using PCR followed by sequence analysis, and we report a further two clinical cases in dogs with recent history of travel to Italy and France. In view of the presence in the UK of the vector for Thelazia callipaeda, namely Phortica ...

Although major advances in the care of cancer patients over the past several decades have resulted in improved survival, infectious complications remain a significant cause of morbidity and mortality. To successfully identify, treat, and prevent infections, a comprehensive understanding of risk factors that predispose to infection and of commonly encountered pathogens is necessary. In addition,...

WE PREVIOUSLY reponed our experience of infectiOUS complications occurring following liver transplantation (OLT) under an experimental immunosuppressive agent FK 506. I In February 1990 we initiated a randomized trial comparing this new drug to cyclosporine (eyA) in patients undergoing their first OLT. In this repon we analyzed the infectious complications in the first 110 patients enrolled in ...