Background: In recent years, neoadjuvant chemoradiation and subsequent surgical resection with total mesorectal excision has been shown to increase local control with decreased toxicity. Neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. In this study we evaluated the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute tox...

IMPORTANCE Nonanatomic factors, such as histologic grade and biomarkers, can guide breast cancer management but are not included in the current TNM staging system. OBJECTIVE To use as an example the triple-negative phenotype (TNP) defined by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor 2 (HER2) to examine whether such inclusion improves ...

OBJECTIVE We sought to determine the impact of positron emission tomography/computed tomography (PET/CT) on the management of presumed resectable pancreatic cancer and to assess the cost of this new staging procedure. SUMMARY BACKGROUND DATA PET using 18F-fluorodeoxyglucose (FDG) is increasingly used for the staging of pancreatic cancer, but anatomic information is limited. Integrated PET/CT ...

BACKGROUND Linear endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an important minimally invasive procedure for non-small cell lung cancer (NSCLC) staging. It is also a valid method for diagnosing extraluminal lesions adjacent to the tracheobronchial tree. AIM To evaluate our EBUS-TBNA performance regarding diagnostic yield, safety and learning curve for lung c...

Angiosarcoma is a rare entity in breast cancer patients. 18-F-Flourodeoxyglucose (FDG) Positron Emission Tomography/ Computed Tomography (PET/CT) is usually used in breast cancer patients for staging, re-staging and treatment response. Lymphangiosarcoma also called as Stewart-Treves Syndrome can be develop in the following years as a complication after therapy of breast cancer. Imaging and stag...

In many countries, treatment for cancer is performed based on staging systems in which the degree of cancer development is defined objectively. A common staging system is thus needed to compare outcomes. The staging system for colorectal cancer in Japan has been made to enhance consistency with the TNM classification, and the categorization of metastatic lymph nodes and depth of invasion have b...

Abstract Background Cervical cancer is a major public health problem for women. Accurate staging may lead to proper management of cervical cancer. We retrospectively reviewed all patients with who underwent pre-treatment MRI between January 2009 and December 2018 analyzed the correlation clinical staging. Results Correlation overall by percent agreement moderate (73.9%), but kappa coefficient s...

PURPOSE To assess the value of oral effervescent powder (EP) for evaluation of esophageal distension, and for detection and staging of esophageal cancer with contrast-enhanced CT. MATERIALS AND METHODS 84 patients without esophageal pathology and 52 patients with histological confirmed diagnosis of esophageal cancer were included in this prospective IRB-approved study. Half of the patients in...

Purpose: The De Ritis ratio (Aspartat transaminase/alanine transaminase) is a critical prognostic factor for some kinds of malignant tumors. Nevertheless, the ratio’s value in preoperative colon cancer staging unclear. purpose this research was to determine and its significance cancer.
 Materials Methods: clinicopathological data 271 individuals with malign were analyzed retrospectively, f...

The tumor-node-metastasis (TNM) staging system for lung cancer has been modified since its first edition in the late 1960s. Its seventh edition has been recently published and, for the first time, a truly worldwide database was analyzed in order to propose modifications in the staging. Significant changes have been made in the tumor and metastasis descriptors. Although the recommendations for t...