نتایج جستجو برای: cancer metastasis
تعداد نتایج: 975459 فیلتر نتایج به سال:
Introduction: Insertion or deletion of a guanine in -1607 at promoter region of matrix metalloproteinase-1 enzyme creates two allelic types for this gene in the population: 2G and 1G, respectively. 2G allele contains an extra binding site for ETS transcription factors that this may increase the level of gene expression. Therefore, aim of this study was investigation of the single Guanine insert...
Background: Mediterean region. Disease-free survival is common to evaluate the treatment of cancers. Severalfactors have been determined as prognostic factors for disease-free survival in studies.Breast cancer is the most common cancer among women especially in easternMethods: in Fayazbakhsh hospital, Tehran. These patients had no metastasis at the time of diagnosis. Patientsunderwent MRM or BC...
Background and Aim: Considering the high global incidence of skin cancer and the high mortality rate caused by melanoma, it is important to identify the genes involved in this disease and predict effective drugs. Therefore, in this study, we have identified and investigated the expression level of effective and key genes in melanoma metastasis, as well as investigating their diagnostic potentia...
background: contralateral axillary metastasis (cam) is a rare entity in patients with breast cancer which can occur during the primary breast cancer or its follow-up. different treatment modalities include surgery, radiotherapy, and chemotherapy, but there is no agreement on them. in our review, we found 12 series with available data, 82 patients with synchronous or metachronous contralateral a...
the gastric cancer in iran is the fourth in the general population. this study was designed to determine the five-year survival rate of gastric cancer patients, and to assess its associated factors. we analyzed the data using a time-dependent covariates model, and recommend it for analyses of similar data. 281 gastric cancer patients with adenocarcinomatous pathology who had been operated on at...
A case of iris metastasis secondary to prostate cancer is reported and the clinical features of the patient are described. A 75 years old man referred with a right iris tumor , secondary glaucoma and severe anterior uveitis. He had history of multiple bone metastases due to prostate cancer. The iris tumor was diagnosed as prostate cancer metastasis and the literature was searched using medline ...
Background: A soluble form of HER-2/neu extracellular domain (sHER-2) is reported to be released in the sera of metastatic breast cancer patients. Objective: To measure the level of sHER-2 in sera of 115 breast cancer patients. Methods: Serial samples of 27 patients with metastasis, 18 non-metastatic patients, 15 patients in stage 0/I and 14 patients with accompanying benign breast disease were...
The lung cancer is one of the most dangerous cancers and is also the leading cause of cancer death worldwide, accounting for about 1.3 million deaths annually. However in clinical practice, lung cancer therapies commonly do with chemotherapy, although it is hard because the lung cancer may progress to metastasis stage. The metastasis of lung cancer is highly dependent of expression of matrix me...
Background and Objectives: The incidence of rectal cancer is increasing in developing societies, especially in younger age groups. The aim of this study was to evaluate the factors affecting the survival of patients with rectal cancer in the presence of competing risks. Methods: In this retrospective cohort study, the data of 121 patients with rectal cancer during 2001-2017 were studied. De...
Objective(s): A growing body of evidence indicates that rhomboid domain containing 1 (RHBDD1) plays an important role in a variety of physiological and pathological processes, including tumorigenesis. We aimed to determine the function of RHBDD1 in breast cancer cells. Materials and Methods: In this study, we used the Oncomine™ database to determine the expression patterns of RHBDD1 in normal a...
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