نتایج جستجو برای: calorie restriction
تعداد نتایج: 78389 فیلتر نتایج به سال:
OBJECTIVE This work analyzed the renal function and structure in offspring rats that were submitted to maternal protein-calorie restriction during prenatal or lactation periods. STUDY DESIGN Kidneys from adult offspring were studied. Animals from mothers that were submitted to food restriction were separated in 3 groups: control, prenatal restriction, and lactation restriction. Blood pressure...
INTRODUCTION: Calorie restriction (CR) is the most effective way known to extend the lifespan of various organisms including yeast, worms, rodents and monkeys. It has been proved that CR could extend lifespan by inducing SIRT1 expression. SIRT1 is an enzyme with NAD-dependent histone deacetylase activity, and the expression of SIRT1 plays an important role in energy metabolism by regulating the...
Fighting diseases and controlling the signs of ageing are the major goals of biomedicine. Sirtuins, enzymes with mainly deacetylating activity, could be pivotal targets of novel preventive and therapeutic strategies to reach such aims. Scientific proofs are accumulating in experimental models, but, to a minor extent, also in humans, that the ancient practice of calorie restriction could prove a...
Although calorie restriction and alternate-day fasting have potential for slowing the aging process while decreasing risk for vascular disease, diabetes, cancer and dementia, a “carbohydrate-concentrated” diet strategy, entailing long daily periods of carbohydrate abstinence, may prove to be a much more practical strategy for achieving these aims. The life extension and healthy aging benefits o...
With our aging society, more people hope for a long and healthy life. In recent years, researchers have focused on healthy longevity factors. In particular, calorie restriction delays aging, reduces mortality, and extends life. Ghrelin, which is secreted during fasting, is well known as an orexigenic peptide. Because ghrelin is increased by caloric restriction, ghrelin may play an important rol...
Marasmus is a severe form of protein-calorie malnutrition characterized by the depletion of fat stores, muscle wasting, and the lack of edema. In developed countries, marasmus is often the result of anorexia nervosa. Abnormal transaminases with liver synthetic dysfunction have rarely been reported with anorexia nervosa. To our knowledge, we report the first detailed case of acute liver injury w...
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