BACKGROUND Patients with myeloproliferative neoplasms (MPNs) are at increased risk for atherothrombotic events. Our aim was to determine if patients with essential thrombocytosis (ET), a subtype of MPNs, free of symptomatic atherosclerosis, have greater carotid artery stiffness, worse endothelial function, greater coronary calcium and carotid plaque burden than control subjects. PATIENTS AND ...

Background and Aim: This study assessed the salivary calcium level, salivary flow rate, and dental problems of patients with Sjogren’s syndrome. Materials and Methods: This case-control study was conducted on 30 patients with Sjogren’s syndrome and 30 healthy controls. The salivary flow rate, salivary calcium level, and the decayed, missing, and filled surfaces (DMFS) index were recorded. ...

BACKGROUND Arterial calcium as measured by 64-slice computed tomography coronary angiography (64-CT) is a reliable predictor of cardiovascular disease risk. Lipid-rich plaques with lower degrees of calcification may pose greater risk for adverse coronary events than more stabilized calcified plaques as a result of the increased risk of plaque rupture, migration, and subsequent acute coronary sy...

The primary use of coronary artery calcium scoring has been in its ability to predict coronary artery disease (CAD) events in generally asymptomatic patients and to provide incremental risk stratification beyond the use of traditional clinical risk factor assessment. Thresholds of calcium burden, as determined by the area-density scoring or Agatston scoring method, on the basis of age, sex, and...

Background—Prognostic risk models have had limited success in predicting coronary events in subjects with multiple risk factors. We and others have proposed an alternative approach using radiographically detectable coronary calcium. We evaluated and compared the predictive value of these 2 approaches for determining coronary event risk in asymptomatic adults with multiple coronary risk factors....

OBJECTIVES This study sought to determine whether noninvasive quantification of coronary calcium is comparable to selective coronary angiography in measuring the effect of cardiovascular risk factors on coronary atherosclerosis. BACKGROUND Electron beam computed tomography (EBCT) allows the delineation of anatomic coronary atherosclerotic disease and may be useful for noninvasively defining t...

BACKGROUND Prognostic risk models have had limited success in predicting coronary events in subjects with multiple risk factors. We and others have proposed an alternative approach using radiographically detectable coronary calcium. We evaluated and compared the predictive value of these 2 approaches for determining coronary event risk in asymptomatic adults with multiple coronary risk factors....

OBJECTIVE We investigated whether regional coronary calcium score by computed tomography is related to regional left ventricular systolic function measured by MRI tagging in participants of the Multiethnic Study of Atherosclerosis. METHODS AND RESULTS The Multiethnic Study of Atherosclerosis is a prospective observational study of men and women without a history of previous heart disease from...

PURPOSE Coronary artery calcium (CAC) is a specific indicator of and an independent risk factor for atherosclerosis; however, calcium scoring may miss noncalcified plaques, which may have clinical importance. The aim of this study was both to identify the presence and extent of coronary plaques during computed tomography coronary angiography (CTCA) in patients with a zero CAC score and to evalu...