INTRODUCTION An analysis of lead, zinc, cadmium and other trace elements in semen of men from infertile couples was performed to determine the association between abnormal semen parameters and enviromental or occupational exposure to some trace metals. MATERIAL AND METHODS Presence of manganese, cobalt, nickel, copper, zinc, molybdenum, cadmium, tin and lead was measured in seminal plasma of ...

This study carried out an assessment of sanitary risks connected to the consumption of Senna rotundifolia Linn. contaminated with lead and cadmium. This plant was collected and analyzed by atomic absorption spectrophotometry. The results revealed a contamination of plants from markets of Dantokpa, Vossa, and Godomey with heavy metals. Senna from Vossa was higher in cadmium and lead levels (Pb: ...

Hypoxia is a common characteristic of solid tumors. Previous studies have reported that the tumor invasion-associated factor, AMPK-related protein kinase 5 (ARK5), is associated with a poor prognosis in colon cancer. However, whether or not ARK5 is involved in hypoxia is unclear. The aim of present study was to investigate the association between the expression of ARK5 and that of hypoxia-induc...

Introduction A continuous oxygen supply is pivotal for tissue development, regeneration, proper maintenance, and homeostasis of the body. During oxidative phosphorylation oxygen (O2) is necessary for the cells to produce ATP. This process produces higher energy than glycolysis. O2 is an essential element for cell survival, membrane transport, regulation of cell signaling, and gene expression. D...

Although it has been shown that HIF1 and 2 fulfill essential roles within the hematopoietic system and in the regulation of HSC fate, little is currently known about the specific mechanisms that are involved. We identified transcriptome changes induced by hypoxia, constitutively active HIF1(P402/564) and HIF2(P405/531) in human cord blood CD34+ cells. Thus, we were able to identify common hypox...

Cadmium is a toxic transition heavy metal with perilous effects on the health of animals and humans by indefinite ways. It one asserted carcinogens group given IARC. There are jillion ways which cadmium may be prevalent in environment as pollutant or through contaminated water, food smoking. poisoning seen form itai disease. came knowledge after its outbreak Japan 1960s consumption cadmium-cont...

Cadmium toxicity interferes with essential metal homeostasis, which is a problem for both plant nutrition and the consumption of healthy food by humans. Copper uptake is performed by the members of the Arabidopsis high affinity copper transporter (COPT) family. One of the members, COPT5, is involved in copper recycling from the vacuole toward the cytosolic compartment. We show herein that copt5...