نتایج جستجو برای: c825t polymorphism
تعداد نتایج: 107359 فیلتر نتایج به سال:
AIMS The goal of our study is to investigate the combined contribution of 10 genetic variants to diabetes susceptibility. METHODS Bibliographic databases were searched from 1970 to Dec 2012 for studies that reported on genetic association study of diabetes. After a comprehensive filtering procedure, 10 candidate gene variants with informative genotype information were collected for the curren...
BACKGROUND AND PURPOSE The C825T dimorphism of the gene encoding the human G protein beta3 subunit (GNB3) is associated with hypertension and obesity. Although these findings suggest an association with insulin resistance and atherosclerosis, this hypothesis has yet been tested only partially. METHODS To investigate this hypothesis, the C825T dimorphism was determined in a population of 932 m...
BACKGROUND Schizophrenia is a common psychiatric disease affecting about 1% of population. One major problem in the treatment is finding the right the drug for the right patients. However, pharmacogenetic results in psychiatry can seldom be replicated. METHODS We selected three candidate genes associated with serotonergic neurotransmission for the study: serotonin 2A (5-HT2A) receptor gene, t...
OBJECTIVE Several epidemiological studies have evaluated the association between the GNB3 C825T polymorphism and hypertension or stroke. The results of these studies were inconsistent; therefore, we performed a meta-analysis to clarify these discrepancies. METHODS We systematically searched the PubMed, Embase, Web of Science, CNKI, and CBM databases, and manually searched reference lists of r...
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