This paper is aimed at evaluating the antioxidant properties of Eugenia Caryophyllata (Syzygium aromaticum), 100% aqueous and 20:80% (water alcohol) for hydroethanolic hydromethanolic extracts were prepared as working solutions studies. About 5 different examinations Syzygium aromaticum (Clove) carried out which include total phenolic content, assay, free radical’s DPPH scavenging activity, hyd...

Epoxide hydrolases (EC 3.3.2.3) (EH) are hydrolytic enzymes which may play an important role in the activation and detoxification of mammary carcinogens. In this study, microsomal, cytosolic, and cholesterol epoxide hydrolases along with glutathione S-transferase were characterized in liver and mammary gland from nulliparous and lactating BALB/c mice and from mice transplanted with preneoplasti...

In this study we tested the genotoxicity of two widely used phenolic antioxidants, butylated hydroxyanisole (BHA) and tert-butylhydroquinone (TBHQ) in multiple mouse organs using the alkaline comet assay. Tissue samples from four organs (stomach, liver, kidney and bone marrow) were collected from male mice at 3 and 24 h post treatment with BHA (800 mg/kg) or TBHQ (400 mg/kg) and examined for ge...

It has been observed that bovine adrenocortical cells in culture fail to synthesize cortisol, while synthesizing deoxycortisol and other precursor steroids. The reason for this loss of activity of 11b-hydroxylase (cytochrome P-450118) was investigated. Treatment of cultures with 30 PM cortisol reduced the half-life of llb-hydroxylase activity from 40 h to 9 h. The concentration of cortisol caus...

Both carcinogenic and anticarcinogenic properties have been reported for the synthetic antioxidants butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT). The association between dietary intake of BHA and BHT and stomach cancer risk was investigated in the Netherlands Cohort Study (NLCS) that started in 1986 among 120,852 men and women aged 55 to 69 years. A semi-quantitative food f...

Bacillus cereus, Clostridium perfringens, Staphylococcus aureus, Pseudomonas fluorescens, Pseudomonas fragi, Escherichia coli, and Salmonella "anatum" were challenged with butylated hydroxyanisole (BHA). Susceptibility was measured as the concentration of BHA required to cause a 90% reduction in bacterial survivors. Staphylococcus aureus LP and P. fragi were two of the most resistant species ex...