Bronchiectasis is a chronic condition in which areas of the bronchial tubes become permanently widened predisposing lungs to infection. an age-associated disease with highest prevalence people older than 75 years. While bronchiectasis higher males, more severe females who have poorer prognosis. The overall thought be rising. Its aetiology multi-faceted, but compromised immune system now play ce...

Abstract Background Pseudomonas aeruginosa is one of the commonest bacteria colonizing airway in patients with non-cystic fibrosis bronchiectasis. colonization associated poor outcomes bronchiectasis, including rapid decline lung function, exacerbation frequency and hospitalization. Methods A cross-sectional study Queen Mary Hospital, Hong Kong that included 350 Chinese bronchiectasis to invest...

OBJECTIVES Bronchiectasis is characterized by an irreversible dilatation of bronchi and is associated with lung fibrosis. MMP-1 polymorphism may alter its transcriptional activity, and differentially modulate bronchial destruction and lung fibrosis. DESIGN To investigate the association of MMP-1 polymorphisms with disease severity in non-cystic fibrosis (CF) bronchiectasis patients, 51 normal...

An unusual case of endobronchial polyposis associated with extensive bronchiectasis in the context of cystic fibrosis (CF) has been described. A 15-yr-old female patient with CF underwent partial pneumonectomy for extensive bronchiectasis and frequent infective pulmonary exacerbations. Cylindrical bronchiectasis with associated purulent bronchitis and bronchiolitis, together with inflammatory p...

BACKGROUND There are limited number of studies investigating extrapulmonary manifestations of bronchiectasis. The purpose of this study was to compare peripheral muscle function, exercise capacity, fatigue, and health status between patients with bronchiectasis and healthy subjects in order to provide documented differences in these characteristics for individuals with and without bronchiectasi...

Bronchiectasis is a constellation of diseases characterized by abnormally dilated bronchi with thickened bronchial walls due to repeated infection and inflammation. Bronchiectasis causes impairment of mucociliary clearance, airflow limitation, bronchorrhea, and predisposes to recurrent respiratory infections. It has a number of potential underlying causes. Laennec first described bronchiectasis...

Bacterial infection of the lung is a cause of bronchiectasis and also the main clinical problem in patients with bronchiectasis. As a consequence, inherited or acquired immunodeficiencies that allow repetitive lung infection with respiratory pathogens (such as Streptococcus pneumoniae and Haemophilus influenzae) can drive the development and progression of bronchiectasis. The immune defects mos...

The association between bronchiectasis and autoimmune disease is well recognised, and best described with rheumatoid arthritis. The prevalence of bronchiectasis in rheumatoid arthritis varies considerably in studies, with obliterative bronchiolitis a common feature. The prognosis of rheumatoid arthritis with bronchiectasis seems to be worse than either condition alone. The advent of high-resolu...