Background: Use of hormone replacement therapy (HRT) may increase the risk of adult-onset asthma in women. Various in vitro studies have reported that estradiol stimulates human mast cell lines causing release of allergic mediators which was not observed in estrogen receptor-alpha (ER-alpha) knockout mice. Thus, estrogen might be a key element in occurrence of asthma. In the present study, we p...

Exhaled nitric oxide (NO) concentration is a noninvasive measure of airway inflammation and is increased in asthma. Inhaled glucocorticoids decrease exhaled NO concentration, but the relative contributions of alveolar and bronchial levels to the decrease in exhaled NO concentration are unknown. Alveolar NO concentration and bronchial NO flux can be separately approximated by measuring exhaled N...

important structures for conditioning luminal gas temperature and humidity. Functionally, nasal vasculature resemble bronchial vasculature in their response to environmental, physical, chemical, nervous and humoral stimuli. M i have extensively studied several factors which regulate nasal airflow resistance(Rnaw)and nasal blood flow(Qn)in man, including nasal or oral hyperventilation and physic...

BACKGROUND Although many patients who experience chest pain or pressure consult their physicians, unfortunately a large number of them do not, and consequently they remain undiagnosed and untreated. Chest pain, in a subset of these patients, may be relieved with a bronchodilator or other asthma drugs. METHODS This retrospective study included twenty cases of chest pain that were relieved with...

The outbreak of a new coronavirus infection was officially recognized by the World Health Organization as global pandemic since March 11, 2020. is currently gradually receding, number patients also steadily decreasing. However, these circumstances are not grounds to believe that virus has been definitively and irrevocably defeated. For this reason, world medical community still concerned about ...

The purpose of this study was to determine the clinical significance of changes in the plasma adiponectin concentration in patients with bronchial asthma and to test the association between the single nucleotide polymorphisms (SNPs) rs2241766 and rs1501299 in the ADIPOQ gene and bronchial asthma in the Chinese Li population. We selected 120 cases and 120 controls, and plasma adiponectin, interl...

The prevalence of asthma was studied in a ice hockey team compared with both a floor ball team and the Swiss population. Lung function, bronchial hyperresponsiveness to methacholine, asthma symptoms and exercise-induced asthma were measured in a cross-sectional prospective study. A positive response to the methacholine bronchial provocation test was found in 34.6% of the ice hockey players and ...

BACKGROUND The pathogenesis of asthma is associated with both genetic and environmental factors. Allergen sensitization is an important risk factor in asthma development. AIM To evaluate sensitivity to allergens by using the skin prick test in patients with a diagnosis of bronchial asthma. METHOD Patients with a diagnosis of bronchial asthma followed-up at the Ministry of Health, Diskapi Ch...

unilateral pulmonary artery agenesis (upaa) is a rare congenital anomaly during the 4 th  week of gestational age. it is defined as an absence of pulmonary parenchyma and its supporting artery. a 9-year-old girl was admitted to our hospital because of chronic cough. chest examination showed a decrement in lung sound of right hemi-thorax with expiratory wheeze. chest radiography (cxr) revealed a...

АСТМА ТА АЛЕРГІЯ, No 1 • 2015 Bronchial asthma (BA) and recurrent bronchitis occupy the leading place among chronic and recurrent respiratory diseases in children age. Special importance of problem of these diseases gets in view of the provisions that recurrent respiratory diseases in children is the debut of chronic bronchopulmonary pathology of adult period of life [1, 16]. One of the importa...