نتایج جستجو برای: breast cancer cell line
تعداد نتایج: 2671475 فیلتر نتایج به سال:
Chaharmahal and Bakhtiari province is a most important endemism states of flora of Iran with a considerable plant species diversity in the country. In the present study the cytotoxic activity of 13 plant species grown in Chaharmahal and Bakhtiari have been evaluated on prostate (PC-3), breast (MCF-7), liver (HepG2), ovary (CHO) and melanoma (B16-F10) cancer cell lines. The cytotoxicity and apop...
Background & Aim: Silibinin is a blend of flavonoids, which is extracted from Marianum Silybum, and its anti-cancer effects on breast cells have been studied. The aim of this study was to provide physiochemical evaluation of various formulations of the niosomal system containing silibinin, in order to achieve targeted formulation to better fight breast cancer cells. Methods: Nano-carriers were...
chromanone derivatives demonstrate remarkable cytotoxity against a varieties of cancer cell lines. novel 9-[hydroxy(substitutedphenyl)methyl]-2,2-dimethyl-2,3,8,9- tetrahydro-4h,10h-pyrano[2,3-f]chromene-4,10-diones as glyasperin analogues were synthesized in four steps from known 4-chromone 1. the key step was the preparation of chromane dione 5a by regioselective intramolecular cyclization re...
Background & Objectives: Breast cancer is the most common cancer and the second leading cause of cancer deaths among women. Obesity, hormones, and growth factors are the risk factors for this kind of cancer. One of the changes observed in patients suffering from breast cancer is the elevated Visfatin or nicotinamide phosphoribosyl transferase (NAMPT) in their tumor tissues and blood. The increa...
Breast cancer is recognized as the most common cause of cancer deaths in women. So far, no definite treatment has been identified there is no certain cure for breast cancer. The Ooverexpression of interleukin-8 is associated with increased tumor growth and breast cancer metastasis. Hesperetin is a flavonone sub-group of flavonoids that is abundantly found in citrus fruits, including lemons and ...
Studies show that cancer cell invasion or metastasis is the primary cause of death inmalignancies including breast cancer. The existence of cancer stem cells (CSCs) in breast cancermay account for tumor initiation, progression, and metastasis. Recent studies have reporteddifferent effects of cannabinoids on cancer cells via CB1 and CB2 cannabinoid receptors. In thepresent study, the effects of ...
Studies show that cancer cell invasion or metastasis is the primary cause of death inmalignancies including breast cancer. The existence of cancer stem cells (CSCs) in breast cancermay account for tumor initiation, progression, and metastasis. Recent studies have reporteddifferent effects of cannabinoids on cancer cells via CB1 and CB2 cannabinoid receptors. In thepresent study, the effects of ...
Abstract Background: Taking into account the resistance of cancer cells to chemical drugs and considering the various reports on the effects of plants from the genus Artemisia for the cure of various ailments and diseases, this investigation was undertaken to compare the cytotoxic effects of different plant organs collected from low and high altitudes. In this study the cytotoxicity of metha...
Background and Objective: Use of nano-carriers that contain plant cytotoxic compounds instead of common chemotherapy drugs can reduce many of the challenges in front of this method of cancer therapy. In this study, surfactant nano-systems containing pomegranate peel extract were designed to evaluate its cytotoxic effects on MCF-7 cell line (breast cancer) and investigated its physicochemical pr...
Background: Electroporation is a valuable tool for small interfering RNA (siRNA) delivery into cells because it efficiently transforms a wide variety of cell types. Since electroporation condition for each cell type must be determined experimentally, this study presents an optimal electroporation strategy to reproducibly and efficiently transfect MDA-MB 468 human breast cancer cell with siRNA. ...
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