Thrombolytic therapy, also known as clot busting drug, is a breakthrough treatment which has saved untold lives. It has been used in the clinical area to treat venous and arterial thromboembolic complaints which are a foremost cause of death. In 1761, Morgagni lead the way of thrombolytic therapy. Now day's different types of thrombolytic drugs are currently available in market: alteplase, anis...

10.1586/14750708.3.6.699 © 2 Characterization of the factor VIII (FVIII) gene and expression of factor VIII through recombinant technology paved the way for the availability of recombinant factor VIII (rFVIII) for intravenous infusion, a significant breakthrough in the treatment of hemophilia A. Kogenate® FS (rFVIII-FS) is a native, full-length factor VIII molecule, produced from a baby hamster...

the miscible displacement process appears to be an increasingly feasible method for the extraction of oil from depleted reservoirs. how­ever, there is a lack of fundamental understanding of how fracture geometrical characteristics impact the oil recovery efficiency in this type of enhanced oil recovery technique. in this work, a series of experimental tests were conducted whereby the n-heptane ...

We present an experimental and theoretical study of the breakthrough performance of the flexible metal-organic framework Cu(bpy)2(BF4)2 (bpy = 4,4'-bipyridine), termed ELM-11. Pure CO2, He, CH4, and N2 gases, as well as binary gas mixtures of those species, were used to perform breakthrough experiments on ELM-11. ELM-11 exhibits a stepped breakthrough curve for CO2 not seen in rigid adsorbents....

The aim of this study was to evaluate the usefulness of serum (1,3)-beta-D-glucan (BDG) for earlier detection of breakthrough candidemia. We reviewed the medical records of patients with candidemia from January 2008 to March 2013. Serum BDG was measured by Wako turbidimetric assay. During the study period, a total of 147 cases of candidemia were identified, and 31 patients met the criteria for ...

BACKGROUND This pilot study evaluates the efficacy of norethisterone acetate in treating pain and gastrointestinal symptoms of women with colorectal endometriosis. METHODS This prospective study included 40 women with colorectal endometriosis, who had pain and gastrointestinal symptoms. Patients received norethisterone acetate (2.5 mg/day) for 12 months; in case of breakthrough bleeding, the ...

The Guidance provides information for clinicians on the steps to be taken before providing a woman with her first prescription for combined oral contraception. It updates and replaces previous Faculty Guidance. A key to the grades of recommendations, based on levels of evidence, is given at the end of this document. Details of the methods used by the Clinical Effectiveness Unit (CEU) in develop...

OBJECTIVE To determine cycle control, safety, and acceptability of a 24-day oral contraceptive regimen containing 15 micrograms of ethinylestradiol and 60 micrograms of gestodene. MATERIAL AND METHOD This was an open-label, non-comparative study. Healthy women 18 to 35 years old who attended the Family Planning Clinic of King Chulalongkorn Memorial Hospital were assigned to receive six cycles...

BACKGROUND The purpose of this study was to determine attitudes to, and provision of, extended regimens for taking the combined oral contraceptive pill (COC) by specialist contraception practitioners from three contrasting specialist contraception services in London. METHODS An online cross-sectional survey was administered to all doctors and nurses, who counsel, provide, or prescribe the ora...