STUDY OBJECTIVE Computed tomography (CT) is frequently used in evaluating children with blunt head trauma. Routine use of CT, however, has disadvantages. Therefore, we sought to derive a decision rule for identifying children at low risk for traumatic brain injuries. METHODS We enrolled children with blunt head trauma at a pediatric trauma center in an observational cohort study between July ...

J. Chen et al. (eds.), Immunological Mechanisms and Therapies in Brain Injuries and Stroke, Springer Series in Translational Stroke Research, DOI 10.1007/978-1-4614-8915-3_2, © Springer Science+Business Media New York 2014 Abstract Acute brain injuries elicit prompt and robust immune responses characterized by the activation of local glial cells and mobilization of peripheral leukocytes. The ac...

OBJECTIVE Young skiers are at increased risk for injury, however, epidemiological data on skiing related fatal injuries among child skiers are scarce. This study aimed to provide information needed to develop injury control and prevention programs. DESIGN AND SETTING Study subjects came from Colorado, USA and were identified using a death certificate based surveillance system. Fatal injuries ...

one hundred patients underwent elective cranioplasty for high velocity missile injury of the head during a 30-month-period study and investigation in amiralmomenin hospital affiliated to iran university of medical sciences. deep penetrating wounds were the most frequent injuries seen during this study. three patients presented with massive bone defects and progressive neurological deficit and d...

The discovery of a continuous renewal of neurons in adult mammalian brains, in particular in the adult hippocampus, has been a breakthrough in Neuroscience. By virtue of the structure-function relationships, this adult hippocampal neurogenesis has been involved in learning and memory. Supporting this hypothesis, a reciprocal relationship between neurogenesis and memory has been evidenced. On on...

Traumatic brain injury (TBI) is an important cause of death with a significant worldwide percentage. In the United States, there are approximately 2.8 million TBIs yearly 250,000 hospitalized patients and 50,000 TBI-related deaths. Every year, one hospitalizations in European Union, resulting more than deaths, most which occur due to road traffic accidents. Needless say, these estimations varie...

post-traumatic epileptic seizure is a common complication of brain trauma including military injuries. we present clinical characteristics and correlates of post-traumatic epilepsy in 163 head-injured veterans suffering from intractable epilepsy due to blunt or penetrating head injuries sustained during the iraq-iran war. the medical records of 163 war veterans who were admitted by the epilepsy...

BACKGROUND Data limited to emergency department and inpatient visits undoubtedly underestimate the medical charges associated with traumatic brain injury. The objective of this study was to estimate the direct medical charges of pediatric traumatic brain injuries across all clinical settings in one large, pediatric hospital in the United States. METHODS Traumatic brain injuries sustained by c...