Spontaneous activity drives the establishment of appropriate connectivity in different circuits during brain development. In mouse primary visual cortex, two distinct patterns spontaneous occur before vision onset: local low-synchronicity events originating retina and global high-synchronicity cortex. We sought to determine contribution these jointly organize network through activity-dependent ...

Background/Aim.Since 2014 and the publication of results first study on accumulation gadolinium contrast, we have witnessed a growing body evidence deposition retention in brain after use gadolinium-based contrast agents (GBCAs). However, there is still no strong clinical adverse effects GBCAs brain. The aim was to determine existence deposits patients with realpsing-remiting (RR) multiple scle...

introduction: a fixed hemodynamic response function (hrf) is commonly used for functional magnetic resonance imaging (fmri) analysis. however, hrf may vary from region to region and subject to subject. we investigated the effect of locally estimated hrf (in functionally homogenous parcels) on activation detection sensitivity in a heroin cue reactivity study. methods: we proposed a novel explora...

The brain produces various reactive oxygen species in enzymatic and non-enzymatic reactions as a by-product of metabolism and/or for redox signaling. Effective antioxidant system the cells maintains balance. However, neurons glia from some regions are more vulnerable to oxidative stress ischemia/reperfusion, epilepsy, neurodegenerative disorders than rest brain. Using fluorescent indicators liv...

It is new clear that the brain of headache sufferers are different from those people without headache, theimaging study showed thickening in specific area related to communication sensory processingcalled somatosensory cortex (post central region) this we examine 36 patient, 28 them haveheadache variable duration, 8 healthy patient used as control (i.e. has no headache). The result foundthat th...

protein amyloid beta (a?), as the pathologic hallmark of alzheimer disease (ad), increases in the brain of diabetic patients. the aim of this study was to investigate the effect of 6 weeks of voluntary wheel running combined with allium paradoxum extract on cortex amyloid beta (a?1-42) levels in diabetic rats induced with alloxan. for this purpose, 42 male wistar rats (weight 185+1 gr, 8 weeks ...

Introduction: Prenatal stress has deleterious effects on the development of the brain and is associated with behavioral and psychosocial problems in childhood and adulthood. This study aimed to determine the protective effect of L-arginine on fetal brain under maternal stress. Methods: Twenty pregnant Wistar rats (weighting 200-230 g) were randomly divided into 4 groups (n=5 for each group). T...

extract  although there are new ways to portray the brain, colored and computerized encephalography but coma is still unknown and such as death remain beyond comprehension and knowing. is not it ?   perhaps because of this, despite knowing that some part of the brain is not yet fully understood all its parts. but knowing the components that working to each other is key for discovering a lot of ...