نتایج جستجو برای: bovine coronavirus
تعداد نتایج: 113598 فیلتر نتایج به سال:
severe acute respiratory syndrome (sars) is a fetal communicable respiratory disease, known as atypical pneumonia. this disease first appeared in china on november 2002 and spread very fast in various parts of the world especially in asia. number of reported cases of sars from november 2002 to may 2003 were about 8046 of which 6825 patients died. sars is caused by coronavirus, and symptoms of d...
Detection and isolation of winter dysentery bovine coronavirus circulated in Korea during 2002-2004.
Although winter dysentery (WD) has been suspected to occur frequently in Korea, to date the exact epidemiology of WD has remained unknown. Therefore, we investigated the causative agents of WD by using electron microscopy, ELISA, RT-PCR, and nested PCR from 97 fecal samples of 32 WD-affected herds collected from 8 provinces during 2002-2004. The bovine coronavirus (BoCV) was consistently detect...
The gene encoding the membrane (M) protein of the OC43 strain of human coronavirus (HCV-OC43) was amplified by a reverse transcription-polymerase chain reaction of viral RNA with HCV-OC43- and bovine coronavirus (BCV)-specific primers. The nucleotide sequence of the cloned 1.5 kb fragment revealed an open reading frame (ORF) of 690 nucleotides which was identified as the M protein gene from its...
Sir—Viruses have evolved various strategies to counteract host-cell processes, notably our immune responses toward their invasion. Oleszak and colleagues reported that the spike proteins of coronaviruses, particularly the mouse hepatitis virus, bovine coronavirus, and transmissible gastroenteritis virus, display Fc gamma receptor activity. Such molecular mimicry of components of our own immune ...
The establishment of persistent viral infection is often associated with the selection of one or more mutant viruses. For example, it has been found that an intraleader open reading frame (ORF) in genomic and subgenomic mRNA (sgmRNA) molecules is selected during bovine coronavirus (BCoV) persistence which leads to translation attenuation of the downstream ORF. Here, we report the unexpected ide...
The synthesis of the negative-strand [(-)-strand] complement of the ∼30 kilobase, positive-strand [(+)-strand] coronaviral genome is a necessary early step for genome replication. The identification of cis-acting elements required for (-)-strand RNA synthesis in coronaviruses, however, has been hampered due to insufficiencies in the techniques used to detect the (-)-strand RNA species. Here, we...
Coronaviruses are positive-strand, RNA-dependent RNA polymerase-utilizing viruses that require a polymerase template switch, characterized as discontinuous transcription, to place a 5'-terminal genomic leader onto subgenomic mRNAs (sgmRNAs). The usually precise switch is thought to occur during the synthesis of negative-strand templates for sgmRNA production and to be directed by heptameric cor...
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