taneous wounds is to eliminate dynamic tension on the healing tissues. Paralysis of the muscle groups adjacent and subjacent to the wound should therefore be as complete as possible. As illustrated in the cases presented herein, the dosages applied for wound healing in the lower face resemble those used for the treatment of spasticity and are substantially larger than those for cosmetic purpose...

In This Issue In This Issue Getting lamin B1 processed and organized amins are the building blocks of the nuclear lamina, a complex polymer attached to the nuclear envelope that is thought to be important for nuclear stability, chromatin organization, and gene expression. On page 1223, Maske et al. identify the protease responsible for processing lamin B1, demonstrate the existence of a nuclear...

PURPOSE To review injection techniques and patient satisfaction with injection of Restylane in various facial areas by American Society of Ophthalmic Plastic and Reconstructive Surgery members. METHODS Data from 286 patients treated with Restylane in nine American Society of Ophthalmic Plastic and Reconstructive Surgery practices were abstracted to a spreadsheet for analysis. RESULTS Nine p...

OBJECTIVES To analyze the predictors of therapeutic efficacy after intravesical botulinum toxin A injection for overactive bladder syndrome (OAB) refractory to antimuscarinic therapy. METHODS All consecutively OAB patients, who visited the urologic outpatient clinics of a medical center and refractory to antimuscarinic treatment, were prospectively enrolled. All enrolled patients received int...

BACKGROUND Cosmetic surgery is becoming increasingly popular in China. However, reports on the predictive factors for cosmetic surgery in Chinese individuals are scarce in the literature. METHODS We retrospectively analyzed 4550 cosmetic surgeries performed from January 2010 to December 2014 at a single center in China. Data collection included patient demographics and type of cosmetic surger...

We investigated whether the eccrine sweat glands must actively produce sweat during heat acclimation if they are to adapt and increase their capacity to sweat. Eight volunteers received intradermal injections of BOTOX, to prevent neural stimulation and sweat production of the sweat glands during heat acclimation, and saline injections as a control in the contralateral forearm. Subjects performe...

AIM The aim of this study was to evaluate the efficacy and safety of a newly manufactured botulinum toxin, Neuronox, compared with BOTOX for the treatment of the spastic equinus gait in children with cerebral palsy. METHOD A total of 127 children with cerebral palsy, aged 2 to 10 years, who presented at three university hospitals with spastic equinus gait were assessed for eligibility to part...