نتایج جستجو برای: borrelia burgdorferi

تعداد نتایج: 6052  

Journal: :Infection and immunity 1997
K Kaneda T Masuzawa K Yasugami T Suzuki Y Suzuki Y Yanagihara

The binding of Borrelia burgdorferi, the causative agent of Lyme disease, to glycosphingolipids present in various types of cells was examined. B. burgdorferi bound specifically to galactosylceramide (GalCer) and glucosylceramide (GlcCer) but not to other glycosphingolipids, as determined by a thin-layer chromatography (TLC) overlay assay. The binding specificity of B. burgdorferi to various gl...

Journal: :Infection and immunity 1998
G H Giambartolomei V A Dennis M T Philipp

Heat-killed Borrelia burgdorferi spirochetes stimulate in vitro production of interleukin-10 (IL-10) at both mRNA and protein levels in peripheral blood mononuclear cells (PBMC) of uninfected rhesus monkeys. A concomitant down-modulation of IL-2 gene transcription was observed. Neither IL-4 nor gamma interferon gene expression was ostensibly affected by B. burgdorferi spirochetes. These phenome...

2011
Stefan S. Tunev Christine J. Hastey Emir Hodzic Sunlian Feng Stephen W. Barthold Nicole Baumgarth

Lymphadenopathy is a hallmark of acute infection with Borrelia burgdorferi, a tick-borne spirochete and causative agent of Lyme borreliosis, but the underlying causes and the functional consequences of this lymph node enlargement have not been revealed. The present study demonstrates that extracellular, live spirochetes accumulate in the cortical areas of lymph nodes following infection of mice...

Journal: :Infection and immunity 2001
A Alitalo T Meri L Rämö T S Jokiranta T Heikkilä I J Seppälä J Oksi M Viljanen S Meri

The most characteristic features of the Lyme disease pathogens, the Borrelia burgdorferi sensu lato (s.l.) group, are their ability to invade tissues and to circumvent the immune defenses of the host for extended periods of time, despite elevated levels of borrelia-specific antibodies in serum and other body fluids. Our aim in the present study was to determine whether B. burgdorferi is able to...

2005
TERRY L. SCHULZE ROBERT A. JORDAN CHRISTOPHER J. SCHULZE TONYA MIXSON MICHELE PAPERO

To evaluate their relative importance in tick-borne disease transmission in New Jersey, host-seeking Amblyomma americanum (L.) and Ixodes scapularis Say adults and nymphs were collected during spring activity periods in 2003 and 2004 to determine relative frequencies at which these ticks were encountered from an area known to be hyperendemic for Lyme disease. Although similar numbers of the two...

2005
Vera A. Rar Natalia V. Fomenko Andrey K. Dobrotvorsky Natalya N. Livanova Svetlana A. Rudakova Evgeniy G. Fedorov Vadim B. Astanin Olga V. Morozova

Ixodes persulcatus (n = 125) and Dermacentor reticulatus (n = 84) ticks from Western Siberia, Russia, were tested for infection with Borrelia, Anaplasma/Ehrlichia, Bartonella, and Babesia spp. by using nested polymerase chain reaction assays with subsequent sequencing. I. persulcatus ticks were infected with Borrelia burgdorferi sensu lato (37.6% +/- 4.3% [standard deviation]), Anaplasma phagoc...

2014
Davide Rolla Novella Conti Francesca Ansaldo Laura Panaro Tiziano Lusenti

INTRODUCTION We report a case of a patient with acute renal failure in Lyme disease-associated focal proliferative mesangial nephropathy. Lyme disease is a vector-borne disease caused by Borrelia burgdorferi, transmitted by the bite of an infected ixodes tick. Post-infectious glomerulonephritis (GN)secondary to Borrelia burgdorferi infection in man could be fatal, as it is in canine Lyme borrel...

2009
Olav Rosef Algimantas Paulauskas Jana Radzijevskaja

BACKGROUND Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum have been considered as pathogens in animals and humans. The role of wild cervids in the epidemiology is not clear. We analyzed questing Ixodes ricinus ticks collected in spring for these pathogens from sites with high (Fjelløyvaer and Strøm) and low density (Tjore, Hinnebu and Jomfruland) of wild cervids to study the spre...

2016
Mariam Meddeb Wassila Carpentier Nicolas Cagnard Sophie Nadaud Antoine Grillon Cathy Barthel Sylvie Josiane De Martino Benoît Jaulhac Nathalie Boulanger Frédéric Schramm

In Lyme borreliosis, the skin is the key site for bacterial inoculation by the infected tick and for cutaneous manifestations. We previously showed that different strains of Borrelia burgdorferi sensu stricto isolated from tick and from different clinical stages of the Lyme borreliosis (erythema migrans, and acrodermatitis chronica atrophicans) elicited a very similar transcriptional response i...

Journal: :Journal of clinical microbiology 2001
A N Alekseev H V Dubinina I Van De Pol L M Schouls

The presence and distribution of Ehrlichia spp. and Borrelia burgdorferi sensu lato was demonstrated among ixodid ticks collected in the Baltic regions of Russia, where Lyme borreliosis is endemic. A total of 3,426 Ixodes ricinus and 1,267 Ixodes persulcatus specimens were collected, and dark-field microscopy showed that 265 (11.5%) I. ricinus and 333 (26.3%) I. persulcatus ticks were positive....

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