today’s tissue engineering is an important and interested method to treatment of  bone lesions so tissue engineering specialists and orthopedic surgeons are forced to serve as a safe alternative to current methods.the introduction ofa scaffoldthathas thebestefficiencyisamajor challengeto scientistsand researchersin this field.the aim ofthisstudy is to investigatethe polyaniline(pani) influence ...

Given the multi-tissue aspects of osteoarthritis (OA) pathophysiology, translation OA susceptibility genes towards underlying biological mechanism and eventually drug target discovery requires appropriate human in vitro models that incorporate both functional bone cartilage tissue units. Therefore, a microfluidic chip is developed with an integrated fibrous polycaprolactone matrix which neo-bon...

Human bone is susceptible to damage from infections, fractures, and diseases. They do, however, have an amazing ability repair themselves after being exposed such factors, which accomplished by a dynamic process of remodeling, maturation, differentiation, regulated resorption. Larger defects, on the other hand, cannot be fully restored because their sizes exceed capacity bones repair. In cases,...

Cells that make up the bodychr('39')s tissues are usually three-dimensional architecture, the threedimensional culture system enables cells to create natural and in vivo interactions which is an ideal environment for 3D (Three-dimensional) cell growth and issues such as exchange of similar food exchanges inside Capillary in living tissue. In tissue engineering discussion, cell scaffolding is hi...

background and aims. statins, the mevalonate pathway inhibitors, have effects on bone formation in vitro and in vivo. the aim of the present study was to investigate whether injection of statins could lead to ectopic bone formation in rats. materials and methods. a single dose (0.5 mg) of simvastatin, atrovastatin, lovastatin and polyethylene glycol (control material) were injected into four qu...

Electrically conductive bone scaffolds composed of carbon-based materials are proposed as promising biomaterials for tissue engineering solutions.

An overview of nanobioceramics-reinforced chitosan combined with cells and growth factors for bone tissue engineering applications.

this study was perfomed on twenty five teeth which showed radiographic lesions( 6mm over 25 mm). the teeth were arranged in seven different groups and root canal therapy ( by warm gutta-percha technique) as surgical intervention were performed at various time intervals. in this investigation, histologic studies of the periapical tissues begin shortly after elimination of the root canal system w...