Osteoporosis is a disease commonly encountered in the general practice, and considered a common cause of fractures mainly among women.it is also an important public health problem in elderly men, so about thirty percent of fractures of hip occur in men.several risk factors have been incriminated in the causation of the disease including age, hypogonadism, drug containing steroid, tobacco smokin...

CONTEXT Calcium Nephrolithiasis is a multifactorial disease; in its pathophysiology is involved various minerals and metabolic factors that may be altered, including bone and phosphor-calcium metabolism. OBJECTIVE To establish the scientific evidence and demonstrate the relationship between calcium nephrolithiasis and bone mineral density loss, through the use of bone turnover markers, serum ...

Bone is a dynamic tissue that provides mechanical support, physical protection, and enables movement. Bone also serves as a storage site for minerals and is where blood cells are produced. Bone homeostasis is regulated by the balance between bone formation and resorption, and involves the coordinated action of osteoblasts and osteoclasts. Osteoblasts are bone-forming cells that secrete organic ...

The date palm is widely known as a richer nutritional source and natural medical agent. Date fruit major of carbohydrates dietary fiber, it has contains proteins, minerals, vitamins, phenolic compounds, carotenoids, sterols, triterpenoids. beneficial potential this well in Arab countries even the world. many health benefits such Glucose-lowering potential, anti-cancer activity, antioxidant hypo...

Electrospun polymeric fibers have been investigated as scaffolding materials for bone tissue engineering. However, their mechanical properties, and in particular stiffness and ultimate tensile strength, cannot match those of natural bones. The objective of the study was to develop novel composite nanofiber scaffolds by attaching minerals to polymeric fibers using an adhesive material - the muss...

Background: Diabetes may influence the bone in multiple pathways, some with contradictory effects. These mechanisms include changes in insulin and hypercalciuria, phophatemia, hypomagnesaemia associated with glycosuria. We tried to find out level of minerals in first degree relatives of patients with diabetes mellitus as there is relationship between bone minerals and glycemic controls. Methods...

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) is a well-established technique in material sciences but has not yet been widely explored for implementation in life sciences. Here, we demonstrate the applicability and advantages of ToF-SIMS analysis for the study of minerals and biomolecules in osseous tissue. The locally resolved analysis of fragment ions deriving from the sample sur...

This study reports the presence of a high molecular weight protein (Bengalin) from the Indian black scorpion (Heterometrus bengalensis) venom having antiosteoporosis activity in experimental osteoporosis developed in female albino Wister rats. Bengalin was purified through DEAE-cellulose ion exchange chromatography and high performance liquid chromatography. The molecular weight of the Bengalin...

Clinical research indicates that negative calcium balance is associated with low bone mass, rapid bone loss, and high fracture rates. However, some studies revealed that not only calcium is involved in bone strengthening as risk factor of fracture osteoporosis. Thus, in this report, the difference of metallic and nonmetallic elements in osteoporosis and normal bones was studied by high-resoluti...

PURPOSE Fibronectin (FN) has been shown to stimulate bone regeneration in animal models. The aim of this study was to evaluate the capacity of bovine bone mineral coated with synthetic oligopeptides to enhance bone regeneration in rabbit calvarial defects. METHODS Oligopeptides including fibrin-binding sequences of FN repeats were synthesized on the basis of primary and tertiary human plasma ...