We previously reported that macrophage exposure to attenuated strains of pathogenic mycobacteria at multiplicities of infection (MOI) < or = 10 triggers TNF-alpha-mediated apoptosis which reduces the viability of intracellular bacilli. Virulent strains were found to suppress macrophage apoptosis, and it was proposed that apoptosis is an innate defense against intracellular Mycobacterium tubercu...

Computational methods involving virtual screening could potentially be employed to discover new biomolecular targets for an individual molecule of interest (MOI). However, existing scoring functions may not accurately differentiate proteins to which the MOI binds from a larger set of macromolecules in a protein structural database. An MOI will most likely have varying degrees of predicted bindi...

OBJECTIVE Monitoring of influenza virus shedding and optimization of multiplicities of infection (MOI) is important in the investigation of a virus one step growth cycle and for obtaining a high yield of virus in vaccine development and conventional basic diagnostic methods. However, eluted infectious viruses may still be present immediately after virus inoculation and when cells are washed fol...

This study reports a lentiviral gene transfer protocol for efficient transduction of adult human peripheral blood (PB)-derived CD34+ NOD/SCID-repopulating cells (SRCs) using vesicular stomatitis virus-G protein (VSV-G)-pseudotyped lentiviruses encoding for enhanced green fluorescence protein (eGFP). Lentiviral stocks were concentrated by anion exchange chromatography, and transduction was perfo...

The choice of an aggregation function is a common problem in Multi Attribute Decision Making (MADM) systems. The Method of Imprecision (MoI) is a formal theory for the manipulation of preliminary design information that represents preferences among design alternatives with the mathematics of fuzzy sets. The MoI formulates the preliminary design problem as a MADM problem. To date, two aggregatio...

MR 2 variety mulberry leaves were sterilized with UV light for 5, 10 and 15 minutes. These leaves were fed to PM x NB 4 D 2 hybrid silkworm Bombyx mori Linn. life stages and recorded the macromolecular contents (total protein, reducing sugar and glycogen) and digestive enzymes (amylase, invertase and protease) activities. Results revealed feeding of silkworm B. mori with UV treated mulberry lea...

À travers ces 12 notules je cherche à montrer comment l’auteur Bharath Murthy a su développer une BD « scientifique » ici plus concrètement philosophique sur lla présence-absence d’une essence appelée âme (ou moi », soi dieu etc.) dans la tradition occidentale et réaffirmée jusque l’IA par certains, déconstruite l’« emptiness aporétique bouddhique en utilisant les techniques spécifiques de band...

Magneto-optic imaging (MOI) is a relatively new technology that produces analog images of magnetic flux leakage from surface and subsurface defects. An alternating current carrying foil serves as the excitation source and induces eddy currents in a conducting test specimen. Under normal conditions, the associated magnetic flux is tangential to specimen surface. Anomalies in the specimen result ...