Figure 3. Toxicokinetic profiles for PCB-153, PCB-180, and HCB blood concentration for (A) normal body weight history and 10 ng/kg/day exposure to each of these chemicals for a woman who was not breast-fed in childhood (blue line) or breast-fed for 6 months (black line); (B) normal weight (gray line), weight loss (black line), or overweight (blue line) profiles and 10 ng/kg/day exposure to each...

The flowers of Butea monosperma are used for curing infertility in local tribes. However the validity has not been scientifically proven therefore the present study is aimed to evaluate the effect of methanolic flower extract of B .monosperma on male albino rat, Rattus rattus (Wistar). The extract of 100, 200 and 300 mg/ kg body weight were administered for 15 days and sacrificed. The weight of...

BACKGROUND Litramine (IQP-G-002AS) was shown to be effective and safe for weight loss in overweight and obese subjects. However, long-term effectiveness on maintenance of body weight loss has yet to be ascertained. OBJECTIVE To assess effect of Litramine on maintenance of body weight loss. METHODS A double-blind, randomised, placebo-controlled trial on overweight and obese patients was cond...

IMPORTANCE Many claims have been made regarding the superiority of one diet or another for inducing weight loss. Which diet is best remains unclear. OBJECTIVE To determine weight loss outcomes for popular diets based on diet class (macronutrient composition) and named diet. DATA SOURCES Search of 6 electronic databases: AMED, CDSR, CENTRAL, CINAHL, EMBASE, and MEDLINE from inception of each...

BACKGROUND Few studies have prospectively evaluated the impact of highly active antiretroviral therapy (HAART) on body weight and lean body mass (LBM) or explored the impact of baseline immunologic or virological changes on these parameters. METHODS Adult AIDS Clinical Trials Group (ACTG) protocol 892 was a prospective, 48-week, multisite observational study of body composition conducted duri...

Coriandrum sativum L. (CS) seeds are known to possess therapeutic potentials against a variety of physiological disorders. This study assesses acute and sub-chronic toxicity profile of hydro-methanolic extract of CS seeds using OECD guidelines. In acute toxicity study, mice were once orally administered 1000, 3000 and 5000 mg/kg body weight of CS extract. There were no any behavioral alteration...

the present study was aimed at elucidating the protective effect of ferulic acid (fa), a natural polyphenol against nicotine-induced tissue damage, including lung, liver and kidney of experimental rats. female albino rats of wistar stain were used for the experimental study. lung toxicity was induced by subcutaneous injection of nicotine at a dose of 2.5 mg/kg body weight (5 days a week, for 22...

We retrospectively identified 67 patients with severe or morbid obesity (body mass index ≥35 kg/m(2)) who had received intravenous vancomycin at our institution. We observed that an initial dose of 45 to 65 mg/kg vancomycin per day based upon ideal body weight rather than actual body weight was more predictive of initial trough concentrations between 15 and 20 mcg/mL.

Sarcostemma secamone (L.) Bennet an ethnomedicinal plant was studied for its immunomodulatory activity. Immunomodulatory activity of different doses of ethanol extract of Sarcostemma secamone was evaluated in Swiss albino mice. Mice were treated with two doses (150 and 300mg/kg body weight) for 5 days. Body weight, relative organ weight, delayed type hypersensitivity (DTH) response and Haemaggl...

Body Mass Index (BMI) is a weight-to-height ratio used as a quick and easy guide to obesity classification. BMI of 30 or greater is indicative of excess body fat and has been labelled as increasing the risk of degenerative diseases such as cardiovascular disease and diabetes. Body fat percentage is also assessed through skinfold thickness measurement.. The aim of this study was to estimate the ...