Double network (DN) gels are anomalously robust but soft and wet materials, whose maximum stress in compression reaches 30MPa and surface friction coefficient reaches 0.001 simultaneously. The DN gels also have shock absorbency, permeability, and biocompatibility. Thus it is expected that the DN gels will be applied to artificial joints, artificial cartilages, and artificial blood vessels. In t...

A stable, polymerized hemoglobin product has been formulated that overcomes the three traditional hurdles of hemoglobin-based blood substitutes: nephrotoxicity, osmotic diuresis, and blood-borne pathogens. We present a case of a patient with persistent colonic bleeding and a hemoglobin of 2.9 g/100 mL. Since her religious faith prevented her from accepting blood products, we offered a hemoglobi...

linked, polymerized, or conjugated human or bovine hemoglobin (1), and they impart a reddish brown color. Jehovah’s Witnesses will not accept blood fractions (red blood cells, plasma, platelets, granulocytes). Acceptable treatments include crystalloids, vasopressors, and hemostatic products (2). Unlike the point-of-care measurement, the core laboratory included a correction for hemolysis. Becau...

Suppl. 1 – S38 moderate length-dependent polyneuropathy of axonal type. Detailed blood screening studies were negative. Genetic testing revealed the diagnosis of nail-patella syndrome with LMX1B gene mutation on chromosome 9q34. The lack of an identifiable acquired cause and the symmetric, slowly progressive and “painless” nature of the patient’s peripheral neuropathy point toward an inherited ...

Center of Excellence in Sickle Cell Disease, Department of Medicine, Boston University School of Medicine, Boston, MA; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Biostatistics, Boston University School of Public Health, Boston, MA; and Sickle Cell Disease Research Center and Department of Pediatrics, College of Medicine, King Saud Univers...

There are many medications that can be utilized to sedate children undergoing fMR examinations. The most frequently used drugs are chloral hydrate, thiopenthal, phenobarbital, propofol, and fentanyl. These medications have some secondary effects on the electrical and metabolic activity of the cortex, cerebral blood flow(CBF), cerebral blood volume(CBV), and tissue oxygen extraction. These effec...

The value of specially prepared gelatin solutions for intravenous infusion as a plasma substitute in the treatment of shock caused by trauma or hemorrhage is now well recognized. Previous papers from our laboratory (1 to 3) have reviewed the literature on the subject and have presented findings indicating the effectiveness of such solutions in various types of shock encountered in human subject...

Discussion • The proposed architecture and data flow are designed to transform raw HIE data into trustworthy data and improve data integrity by examining data quality attributes of physiological compatibility, completeness, and redundancy. • By filtering out previously processed data and retaining only new HIE data, the architecture eliminates duplicate processing of discrete data from incoming...

Insufficient vascularisation of substitutes in the operative reconstruction of the oesophagus is one of the main causes of the occurrence of anastomotic leaks. In the present study, the blood oxygenation of gastric substitutes for the oesophagus was evaluated before and during the reconstruction. A pulse oximeter was used for the assessment (S&J Medico Teknik AIS, Albertslund, Denmark). Oxygena...