One of the simple and economical diagnostic methods in detecting nasal allergic disorders is cytological examination of nasal smears. This study was conducted to evaluate the usefulness of nasal cytology in individuals suffering from allergic nasal disorders, including allergic nasal polyps with special interest on cytohistological correlation in case of allergic nasal polyps. Effort is also ma...

Blood cell count was performed on an automated analyzer using an ethylenediaminetetraacetic acid (EDTA) blood specimen and showed normal hemoglobin and leukocytes (7.2 109/L), but a mild thrombocytosis (467 109/L). Platelet clumps were flagged by the cell counter. However, when the peripheral smear was reviewed, there was leukocyte agglutination (shown, left) rather than clumps of platelets. Th...

BACKGROUND Approximately 4 million US travelers to developing countries are ill enough to seek health care, with 1500 malaria cases reported in the United States annually. The diagnosis of malaria is frequently delayed because of the time required to prepare malaria blood films and lack of technical expertise. An easy, reliable rapid diagnostic test (RDT) with high sensitivity and negative pred...

The smear layer in endodontically instrumented root canals first reported in 19751 is both organic and inorganic in composition. 2 The inorganic material in the smear layer is composed of tooth structure and some nonspecific inorganic contaminants. 2 The organic components may consist of heated coagulated proteins, necrotic or viable pulp tissue, and odontoblastic processes plus saliva, blood c...

BACKGROUND Although checking specimen quality upon sputum collection for acid-fast smear of suspected tuberculosis (TB) cases is recommended, this procedure is based on expert opinion. The purpose of this study was to elucidate the impact of sputum gross appearance and volume on smear positivity among patients with suspected pulmonary TB, according to sex. METHODS From November 2010 through J...

Malaria presents a diagnostic challenge in most tropical countries like India. Microscopy remains the gold standard for diagnosing malaria, but it is labour intensive and depends upon the skill of the examiner. Malaria rapid diagnostic tests (RDT’s) have been developed as an easy, convenient alternative to microscopy. The aim of this study was to correlate and compare the conventional diagnosti...

BACKGROUND Sputum smear microscopy for tuberculosis (TB) diagnosis lacks sensitivity in HIV-infected symptomatic patients and increases the likelihood that mycobacterial infections particularly disseminated TB will be missed; delays in diagnosis can be fatal. Given the duration for MTB growth in blood culture, clinical predictors of MTB bacteremia may improve early diagnosis of mycobacteremia. ...

The complexity of the cell structure and high overlap causes poor image contrast. Complex imaging factors in lighting differences, dye concentrations, other variables such as drying air, excess blood, mucus, bacteria, or inflammation can make automatic visual interpretation more difficult. This study proposes an approach model by combining basic processing techniques deep learning for segmentat...

Infantile pyknocytosis is a rare cause of neonatal jaundice and hemolytic anemia. We report on two cases in twin girls that were diagnosed on peripheral blood smear reading. Pyknocytosis should be considered in cases of early unexplained severe hemolytic anemia, and systematic peripheral smear review performed. Its management consists of phototherapy and RBC transfusion.

Peripheral Smear (PS) examination still remains a cornerstone and first step towards diagnostic work up of patients. However, presence artefacts in PS can sometimes prove perplexing for the pathologists [1]. In one such experience, early morning blood sample K2 EDTA vial 23 year old female was sent to hematology lab.