Porcine plasma and factor VIII preparations were screened for parvovirus 4 (PARV)-like viruses. Although the prevalence of PARV4-like viruses in plasma samples was relatively low, viruses appeared to be concentrated during manufacture of factor VIII. PARV4-like viruses from human and porcine origins coevolved likewise with their hosts.

1Canadian Blood Services, Ottawa, ON, Canada K1G 4J5 2Research and Development, Australian Red Cross Blood Service, Sydney, NSW, Australia 3Canadian Blood Services, 8249-114 Street, Edmonton, AB, Canada T6G 2R8 4Department of Laboratory Medicine and Pathology, University of Alberta, 8249-114 Street, Edmonton, AB, Canada T6G 2R8 5Canadian Blood Services, Hamilton, ON, Canada 6Department of Patho...

We introduce a real-life problem faced by the blood bank of the Austrian Red Cross for Eastern Austria: how to cost-effectively organize the periodic delivery of blood products to Austrian hospitals. We present various solution approaches, based on integer programming and variable neighborhood search, and empirically evaluate their performance. Moreover, we study the potential value of switchin...

Approximately half of cancer patients scheduled for major surgery are anemic. Also, a significant number of patients will present to the operating room with low platelet counts and coagulopathic disorders. Unfortunately, administration of red blood cells, platelets concentrates and fresh-frozen plasma is associated with unwanted adverse effects including fever, hemolytic reactions and transfusi...

Apart from any fair dealing for the use of private study, research, criticism, or review as permitted under the Copyright Act 1968, no part of this book may be transmitted or reproduced in any form, electronic or mechanical, or by any information storage and retrieval system, without the written permission of the Publishers. 1 st Edition (2004): Australian and New Zealand Society of Blood Trans...

background and aims: human parvovirus b19, a member of the parvoviridae family, with single-stranded dna is a very minute non-enveloped virus. b 19 virus is mostly transmitted via the respiratory tract but some studies have been reported which b19 virus can be transmitted through blood and/or blood products. the aim of this study was to evaluate the prevalence of b19 among blood donors in tehra...