The risk of developing pregnancy-induced hypertension and preeclampsia is higher in obese pregnant women. In obesity, the composition of the gut microbiota is altered. Obesity is also associated with low-grade inflammation. Metabolites from the gut microbiota may contribute to both hypertension and inflammation. The aim of this study is to investigate whether the composition of the gut microbio...

We studied the incidence of cerebral hemorrhage in an animal model of embolic stroke to determine the safety of aspirin, heparin, and tissue plasminogen activator therapies. We occluded the middle cerebral arteries of rabbits with labeled blood clots and administered either tissue plasminogen activator, heparin, aspirin, tissue plasminogen activator plus aspirin, tissue plasminogen activator pl...

was bitten, while collecting grass, 011 the dorsum of the left hand near the root of the middle finger. He ran to the hospital within 15 minutes after the bite. No ligature was put on. The fang marks were visible and slightly bleeding. Acute burning pain at the site. Intense swelling of the hand and fingers. Marked swelling of the fore-arm up to the elbow-joint. Free incisions were made on the ...

Background: Plasminogen activator inhibitor-1 (PAI-1) is a glycoprotein with inhibitory effects on the formation of plasmin from plasminogen by plasminogen activator. Thus, it prevents clot lysis in vessel walls. Several evidences prove the relationship between coronary artery disease and response to fibrinolytic therapy in patients with myocardial infarction with PAI-1 level. Opium addiction i...

The aim of the study is to assess the diagnostic accuracy of some fibrinolytic parameters in the differential diagnosis between patients with unstable angina (UA) and musculoskeletal disorders (MSD). Methods. This cross-sectional study included 119 patients with chest pain (CP) and provisional diagnosis “UA”. After a full set of diagnostic procedures, authors formed 4 groups: patients with isc...

In this review paper, an emphasis is made to focus on the history, source, structure, mode of action, and application Nattokinase. The reveals that Nattokinase can act as a potent thrombolytic agent compared other agents which are commercially available. Studies NK have also be proved it useful for dissolving blood clots by converting plasminogen plasmin, further fibrin clots. been isolated fro...

it has been shown that geopolymerization can transform a wide range of waste aluminosilicate materials into building materials with excellent chemical and physical properties such as fire and acid resistance. in this research work, geopolymerization of construction waste materials with different alkali-activators based on combinations of na2sio3 and naoh has been investigated. a number of syste...

An acidic phospholipase A2 (EC-I-PLA2) has been purified from the Indian saw-scaled viper (Echis carinatus) venom through a combination of column chromatography and electrophoresis. EC-I-PLA2 has a molecular weight of 16000 by SDS-PAGE. It was focussed between pH 4.2 and 4.8 by isoelectro focussing. EC-I-PLA2 was non-lethal to mice and devoid of neurotoxicity, myotoxicity, anticoagulant activit...

The multicatalytic protease (MCP) can be activated by two distinct multisubunit complexes. One is the regulatory component of the 26 S protease, which contains at least 15 distinct subunits. The other is a hexameric activator composed of 31- and 29-kDa subunits. A cDNA for the smaller subunit has been cloned and sequenced. The cDNA encodes a protein of 249 amino acids. Embedded between sequence...