نتایج جستجو برای: blocking antibodies

تعداد نتایج: 206867  

Journal: :Genetics and molecular research : GMR 2015
H Y Gao E X Tao Y Wang Q A Yue C E Ren L F Yan

We studied the immunomodulatory and clinical effects of the empirical formula "tiaomian III decoction" on maternal blood blocking antibody deficiency and recurrent spontaneous abortion. Sixty-one patients with blocking antibody deficiency were divided in the experimental group (N = 31), who took tiaomian III decoction, and the control group (N = 30), who received active immunotherapy with pater...

Journal: :Journal of virology 2008
Penny L Moore Elin S Gray Isaac A Choge Nthabeleng Ranchobe Koleka Mlisana Salim S Abdool Karim Carolyn Williamson Lynn Morris

The early autologous neutralizing antibody response in human immunodeficiency virus type 1 (HIV-1) subtype C infections is often characterized by high titers, but the response is type specific with little to no cross-neutralizing activity. The specificities of these early neutralizing antibodies are not known; however, the type specificity suggests that they may target the variable regions of t...

Journal: :The Journal of infectious diseases 2014
Maria Malm Hanni Uusi-Kerttula Timo Vesikari Vesna Blazevic

BACKGROUND Norovirus is a common cause of acute gastroenteritis in children. Serum immunoglobulin G (IgG) antibodies have been implicated in protection against norovirus-associated gastroenteritis, but the level, specificity, and functionality necessary for protection remain to be elucidated. METHODS Norovirus-specific IgG antibodies to genogroup II (GII)-4-2010 New Orleans (NO), GII-4-1999, ...

2014
Timothy R Hercus Sophie E Broughton Matthew P Hardy Tracy L Nero Nicholas J Wilson Michael W Parker Angel F Lopez

CSL362 is a humanized interleukin-3 (IL-3)-neutralizing monoclonal antibody with enhanced effector function that binds the α subunit of the IL-3 receptor (IL3Rα). The crystal structure of an IL3Rα:CSL362 complex shows that IL3Rα adopts "open" and "closed" conformations. CSL362 blocks IL-3 function through both IL3Rα conformations but via distinct and unexpected mechanisms.

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