Prevention is undeniably the sensible maneuver towards the ultimate goal of cancer control [1]. According to the World Cancer Report released by the World Health Organization (WHO) in 2003 [2], cancer rates could further increase by 50% to 15 million new cases in the year 2020. Chemotherapy, radiotherapy and surgery are commonly used treatment methods for cancer in modern medicine. Chemotherapy...

background: in order to study the biology of mylabris impressa stillata , which little is known about, a laboratory colony was established. methods: in this descriptive study, the laboratory colony was collected from toyserkan county in hamedan province, iran. to feed the larval instars, a parallel colony of the grasshopper, schistocerca gregaria was set-up. meloid females lived for several mon...

In the order Coleoptera, cantharidin is produced by two families, Meloidae (true blister beetles) and Oedemeridae (false blister beetles). Cantharidin is of veterinary and medical importance, since it is super toxic to animals and humans. The present work was conducted aiming to review the cantharidin investigation and cantharidin toxicosis to animals including pathology, symptomatology, preven...

The pharmacokinetics of the quinolone enoxacin were studied after a 600-mg oral dose was given to each of six male volunteers. The levels of the compound were measured in serum, blister fluid, and urine. Absorption was variable, with peak levels (mean, 3.7 micrograms/ml) being attained between 0.75 and 3.0 h (mean, 1.9 h). The serum elimination half-life was 6.2 h, and 71.6% of the drug was rec...

In dystrophic epidermolysis bullosa the genetic defect of anchoring fibrils leads to cleavage beneath the basement membrane, with its consequent loss. We performed scanning electron microscopy of an inverted blister roof of a case of dystrophic epidermolysis bullosa, confirmed by immunomapping and gene sequencing. With a magnification of 2000 times a net attached to the blister roof could be ea...

Abstract. In order to study the effect of carbon impurity in plasma on tungsten first wall, hydrogen-carbon mixed ion beam was irradiated to tungsten. It was found that very small amount of carbon (~0.3% or more) significantly enhanced blister formation. According to XPS analysis, all of tungsten atoms in a top surface were combined with carbon atoms to form tungsten carbide (WC) layer (~6 nm t...

BACKGROUND Mucous Membrane Pemphigoid (MMP) is a rare group of chronic autoimmune disorders characterized by blister producing lesions. It is the variant most likely to occur in the oral cavity and eyes. Few studies shows autoimmune bullous diseases associated with human immunodeficiency virus (HIV). CASE PRESENTATION oral blisters, painful ulcerations and eye symblepharon were observed in a ...

The effect of protein binding on drug penetration into blister fluid was evaluated by using cefonicid, ceftizoxime, and cefotaxime. Drug concentrations in a chamber with a high surface area/volume ratio (i.e., paper disk) follow changes in serum more closely than do those in a chamber with a low surface area/volume ratio. Both the area under the concentration-time curve ratio and the concentrat...

The pharmacokinetics of the new cephalosporin Ro-13-9904 were studied in six healthy male volunteers receiving a 500-mg dose as a bolus intravenously. Tissue penetration of the antibiotic was estimated by using a cantharides blister method. The data obtained fitted a two-compartment open model. The mean elimination half-life was about 8 h, which is considerably longer than that of other beta-la...