background: resistance to contemporary broad-spectrum b-lactam antibiotics mediated by extended-spectrum b-lactamases (esbls) is increasing worldwide. klebsiella pneumoniae , an important cause of nosocomial and community acquired urinary tract infections has rapidly become the most common esbl producing organism. we examined esbl production in urinary isolates of k. pneumoniae in relation to t...

conclusions our data showed that, the high prevalence of beta-lactamase genes among isolates, and it. our findings may provide useful insights in replace of the appropriate antibiotics and it may also prevents of esbls, mediated resistance problem. results from 145 strains of e. coli, 51(35.2%) and 61(42.1%) isolates were resistance to ceftazidime and cefotaxime, respectively. esbl production w...

Methods From a total of 72 non-duplicate quinolone and cephalosporin resistant Enterobacteriacae obtained from October-December 2010 from Ahmadi hospital in Kuwait, 16 were K. pneumoniae. Antimicrobial susceptibility was determined by Vitek, Microscan, double disc diffusion, agar dilution and E-test against a panel of 26 antimicrobial agents. The presence of blaSHV, blaTEM, blaCTX-M, gyrA, parC...

Genetic determinants of a bla(NDM-1)-positive, multidrug-resistant bacterial isolate that caused active infection was investigated by DNA sequencing. Two plasmids, pKOX_NDM1 and pKOX-R1, were identified for the Klebsiella oxytoca strain E718. Sequence annotation revealed a bla(NDM-1) gene in pKOX_NDM1 and two extended-spectrum β-lactamase producers (bla(CTX-M-3) and blaSHV-12) and a wide array ...

BACKGROUND Pseudomonas aeruginosa is the most common pathogen causing nosocomial infections. Resistance of P. aeruginosa strains to broad-spectrum cephalosporins may be mediated by extended-spectrum β-lactamases (ESBLs). OBJECTIVES We intended to investigate the prevalence of ESBLs and antimicrobial susceptibilities of P. aeruginosa isolated from patients in Zahedan, Iran. MATERIALS AND MET...

Bovine mastitis is often taken as one of the most common diseases in dairy farms, which its pathophysiology leads to a reduction milk production and quality. The penetration pathogenic bacteria into mammary gland, through either contagious or environmental approach, has been determined way infection. derived have become challenge practice, since increasing exposure antimicrobial. In order ident...