Lichen planus pigmentosus (LPP) is chronic pigmentary disorder that shows diffuse or reticulated hyperpigmented, dark brown macules on the sun-exposed areas such as the face, neck and other flexural folds. Clinically, it is different from classical lichen planus because LPP has a longer clinical course and it manifests with dark brown macules. In case of LPP, involvement of the scalp, nail or m...

REFERENCES 1. Zulian F. New developments in localized scleroderma. Curr Opin Rheumatol 2008;20:601–7. 2. Maragh SH, Davis MDP, Bruce AJ, Nelson AM. Disabling pansclerotic morphea: clinical presentation in two adults. J Am Acad Dermatol 2005;53(2 Suppl 1):S115–19. 3. Blaschko A. Die Nervenverteilung in der Haut in ihre Beziehung zu den Erkrankungen der Haut. Wien and Leipzig: Braumuller, 1901. 4...

Incontinentia pigmenti (IP) is a rare X-linked dominant neurocutaneous disorder affecting ectodermal tissue: skin, eyes, central nervous system, hair, nails, and teeth. It is usually lethal for males in utero. The involved gene is NEMO, an essential component of the nuclear factor-kappa B (NF-κB) signaling pathway. Skin lesions are highly diagnostic, occurring in neonates, with a particular dis...

Le lichen blaschko-linéaire constitue une forme rare (0,5 %) du lichen plan dont l'âge moyen de survenue est de 50ans. Il est plus fréquent chez l'homme. Sa disposition linéaire en dehors du phénomène de Koebner serait due au mosaicisme génétique responsable de la présence d'un clone kératinocytaire capable de réagir sous l'effet de facteurs immunogènes, exogènes ou infectieux. Le traitement re...

A 34 year man presented to us with itchy lesions on one half of the trunk for the past two months. The lesions started as erythematous to violaceous papules and plaques on the flank and gradually increased in number to involve the left side of the trunk (Figure 1 and 2). Some areas showed the Koebner phenomenon. These lesions were distributed along the lines of Blaschko. Examination of the oral...

INTRODUCTION Incontinentia pigmenti is a rare X-linked dominant disease which affects the ectodermal tissues, usually lethal in males. MATERIALS AND METHODS A retrospective analysis of clinical data obtained from the photographic documentation and casenotes of patients diagnosed to have incontinentia pigmenti at the National Skin Centre. The study covered the period from January 1990 to Decem...