Reactions of O-peracylated C-(1-bromo-β-d-glucopyranosyl)formamides with thioamides furnished the corresponding glucopyranosylidene-spiro-thiazolin-4-one. While O-debenzoylations under a variety of conditions resulted in decomposition, during O-deacetylations the addition of MeOH to the thiazolinone moiety was observed, and with EtOH and water similar adducts were isolated or detected. The stru...

A new D-A-π-A-D molecule (Spiro-BTA) containing two 2,1,3-benzothiadiazole (BTA) as the acceptor (A) and triphenylamine as the donor (D) bridged by a spirobifluorene moiety has been synthesized. The novel D-A molecule shows intense red emission (612 nm) with a high PL quantum yield (Φ(PL) = 0.51) in a solid film. A cyclic voltammogram of Spiro-BTA in 1:2 MeCN:benzene/0.1 M Bu(4)NPF(6) shows two...

sulfonic acid functionalized sba-15 (sba-pr-so3h) with pore size 6 nm as an efficient heterogeneous nanoporous solid acid catalyst exhibited good catalytic activity in the biginelli-like reaction in the synthesis of spiroheterobicyclic rings with good yield and good recyclability. spiro-pyrimidinethiones/spiro-pyrimidinones-barbituric acid derivatives were synthesized in a simple and efficient ...

Synthesis of (4',5'-diaza-9'-fluorene)-spiro-5-hydantoin: The paper presents a method for synthesis of (4',5'-diaza-9'-fluorene)-spiro-5-hydantoin. The newly obtained compound was synthesized by a treatment of 4,5-diazafluoren-9-one with sodium cyanide, ammonium carbonate, ethanol and ammonium hydroxide at high pressure and high temperature. The structure of (4',5'-diaza-9'-fluorene)-spiro-5-hy...

6'-(4-Chlorophenyl)-spiro[cyclohexane-1,2'-thieno[3,2-d][1,3] oxazin]-4'(1'H)-one (1) was synthesized and used as a starting material for the synthesis of a novel series of spiro compounds having biologically active sulfonamide 2a-e and 3'-(4-acetylphenyl)-6'- (4-chlorophenyl)-1'H-spiro[cyclohexane-1,2'-thieno[3,2-d] pyrimidine-4'(3'H)-one (3). Compound 2a was used as a key intermediate for the...

A facile construction of the spiro[indole-3,2'-pyrrolidine] skeleton, through diacetoxyiodobenzene (PIDA) mediated C-N bond-forming dearomatization of C3 sulfonamide linked indole derivatives, has been developed. A variety of spiro-indolepyrrolidines were obtained in moderate to excellent yields under mild conditions.

An exploration of the chemistry of the spiro-mamakone system, exemplified by the cytotoxic, fungal metabolite spiro-mamakone A, is presented. The first reported synthesis of the spiro-mamakone carbon skeleton was achieved, as well as the synthesis of a variety of closely related analogues of the natural product. Biological testing of the synthetic analogues generated a structure-activity profil...