OBJECTIVE To examine the relationship of borderline personality disorder (BPD) to mood disorders by using data from the Collaborative Longitudinal Personality Disorders Study on the reciprocal interactions of BPD with both depressive and bipolar disorders over the course of 10 years. METHOD The study included 223 BPD patients with DSM-IV-defined co-occurring major depressive disorder (MDD) (n...

BACKGROUND/AIMS Temperament and mood swings are promising indicators for the characterization of mood spectrum vulnerability. The aim of this study was to investigate the relationship between affective temperament and mood swings in bipolar disorder. We explored these clinical features retrospectively. METHODS Patients who met the criteria for bipolar I disorder were enrolled in the study. Ex...

BACKGROUND The depressive disorder is one of the most frequent mental disorders, which is often associated with severe dysfunctionality. Personality traits are considered as important factors for the occurrence of depressive disorder. AIM To determine the specificity of personality dimensions as predictive factors of depressive disorder. METHODS This research was conducted at the University...

objective: the present study aims to investigate thought control strategies in generalized anxiety disorder (gad), major depressive disorder (mdd), and the relationship of these metacognitive strategies with trait anxiety, as a construct of emotional vulnerability. methods: 60 patients with diagnosis of gad and mdd and 30 control subjects (nonpatients) were selected from the university students...

Bipolar disorder is a recurring, often chronic, illness characterised by periods of mania and depression with variable inter-episode recovery. For the majority of patients it is the depressive component of this illness that contributes to most of the associated morbidity, social disability and mortality. Research and clinical experience suggest that acute treatment and prevention of depressive ...

Bipolar disorder is a recurring, often chronic, illness characterised by periods of mania and depression with variable inter-episode recovery. For the majority of patients it is the depressive component of this illness that contributes to most of the associated morbidity, social disability and mortality. Research and clinical experience suggest that acute treatment and prevention of depressive ...

INTRODUCTION "We of the craft (poets) are all crazy," remarked the 18th century British romanticist Lord Byron (George Gordon) about himself and his fellow poets. Implied in this statement is the notion that there exists a special kind of relationship between poets and being "crazy". A relationship between psychopathology and the artistic temperament is one of the oldest and most persistent of ...

Major depressive disorder and bipolar disorder share symptoms that may reflect core mood disorder features. This has led to the pursuit of intermediate phenotypes and a dimensional approach to understand neurobiological disruptions in mood disorders. Executive dysfunction, including cognitive control, may represent a promising intermediate phenotype across major depressive disorder and bipolar ...

psychotic disorders and bipolar disorder (8) and between bipolar disorder and major depressive disorder (9). Although family and twin studies can estimate the shared heritability across disorders, they cannot identify the genetic loci contributing to this overlap. To date, evidence implicating specifi c chromosomal regions and genes in the shared liability to psychotic and mood disorders has la...