conclusions these findings support that the careful evaluation and prospective following of the psychopathology of children of parents with bipolar disorder are critical for early identification and treatment. results there were statistically significant differences between children of parents with and those without bipolar disorder regarding attention deficit hyperactivity disorder, opposition...

OBJECTIVE Despite clear gender differences in the symptoms and course of bipolar affective disorder, studies investigating age at onset by gender have yielded inconsistent results. The authors investigated gender differences in age at onset and incidence of first-episode mania and bipolar disorder in an epidemiological catchment area in southeast London over a 35-year period. METHOD All adult...

CONTEXT Affective disorders are common in women, with many episodes having an onset in pregnancy or during the postpartum period. OBJECTIVE To investigate the occurrence and timing of perinatal mood episodes in women with bipolar I disorder, bipolar II disorder, and recurrent major depression (RMD). SETTING AND PATIENTS Women were recruited in our ongoing research on the genetic and nongenetic ...

Bipolar disorder has a genetic component, but the mode of inheritance remains unclear. A previous genome scan conducted in 70 European families led to detect eight regions linked to bipolar disease. Here, we present an investigation of whether the phenotypic heterogeneity of the disorder corresponds to genetic heterogeneity in these regions using additional markers and an extended sample of fam...

OBJECTIVES The aims of the study were to validate the Turkish version of the Mood Disorder Questionnaire (MDQ) as a screening tool and to determine its optimum cut-off value for bipolar disorder. METHODS Validation of the Turkish version of the MDQ was conducted on a sample of 309 consecutive patients who attended the psychiatry outpatient unit of 2 different university hospitals. The Structu...

Positive emotions are vital to attaining important goals, nurturing social bonds, and promoting cognitive flexibility. However, one question remains relatively unaddressed: Can positive emotions also be a source of dysfunction and negative outcomes? An ideal point of entry to understand how positive emotion can go awry is bipolar disorder, a psychiatric disorder marked by abnormally elevated po...

AIM The present study aimed to compare cognitive signs of bipolar disorder patients with that of adult attention-deficit/hyperactivity disorder (ADHD) patients. METHOD The study comprised 66 bipolar disorder patients, 63 ADHD patients, and 58 healthy controls.Structured Clinical Interview for DSM-IV Axis-I Disorders (SCID-I), Wender Utah Rating Scale, and Adult Attention-Deficit/Hyperactivity...

Objective: The study aims to determine pattern of verbal memory and learning impairment and its associated factors among patients with bipolar I disorder in a psychiatric clinic of a university hospital. Methods: A case control study comparing verbal memory test performance in 40 patients with bipolar I disorder to that of 40 healthy normal subjects using Rey Auditory Verbal Learning Test (RAVL...