A pseudogene arises when a gene loses the ability to produce a protein, which can be due to mutation or inaccurate duplication. Previous dogma has dictated that because the pseudogene no longer produces a protein it becomes functionless and evolutionarily inert, being neither conserved nor removed. However, recent evidence has forced a re-evaluation of this view. Some pseudogenes, although not ...

Chugunova, E., 2004. Biological function of mast cell chymase mMCP-4. In vitro and in vivo studies: a thorny pathway. Doctor's dissertation. ISSN 1401-6257, ISBN 91-576-6680-6 Mast cells (MCs) are key effector cells in various types of inflammatory conditions. The MC secretory granules contain inflammatory mediators such as histamine, heparin proteoglycan (PG), cytokines and various heparin-bin...

abstract : the crown-root fracture is a common tooth injury which compromises the biological width and need proper endodontic and prosthodontic treatment to achieve acceptable clinical outcome. this case report describes clinical management of crown-root fracture in maxillary central incisors which was successfully treated by forceps eruption with 180˚ rotation to restore the biological width. ...

background: rna plays key role in many aspects of biological processes and its tertiary structure is critical for its biological function. rna secondary structure represents various significant portions of rna tertiary structure. since the biological function of rna is concluded indirectly from its primary structure, it would be important to analyze the relations between the rna sequences and t...

the discovery of rna interference (rnai) in recent years has revolutionized biological and medical research. rnai is the sequence-specific gene silencing triggered by double-stranded rna (dsrna). until a couple of years ago only biologists working with caenorhabditis elegans and plants could use rnai technology to gain insight into gene function……