Agglomeration of nanoparticles in biological fluids is a pervasive phenomenon that leads to difficulty in the interpretation of results from in vitro exposure, primarily due to differing particokinetics of agglomerates to nanoparticles. Therefore, well-defined small agglomerates were designed that possessed different particokinetic profiles, and their cellular uptake was compared to a computati...

Synthetic diamond is potentially one of the more interesting materials in the field of detectors applicable in dosimetry. It is, in fact, tissue equivalent (its atomic number, Z = 6, is very close to the actual atomic number of a biological tissue, Z = 7.5. Moreover it is not toxic and shows a high resistance to radiation damage, a high sensitivity and stability of response, a low leakage curre...

In this paper the authors discuss a method using 1-nm particulate radon decay products as an experimental tool in the study of local lung deposition and dosimetry for nanoaerosols. The study of aerosol exposure and dosimetry measurements, and related quantitative assessment of health effects, are important to the understanding of the consequences of air pollution, and are discussed widely in th...

Accidents involving human exposure to radiation can cause severe health effects which may require extensive medical resources. Particularly in mass-casualty events, the rapid identification and classification of potentially overexposed individuals into medical treatment groups is of prime importance. For this purpose, clinical signs and symptoms and biological dosimetry methods are the two main...

The Technical Report Series 398 (TRS-398), Electron Dosimetry Working Party (EWDP), and Task Group 51 (TG 51) are the most important protocols for reference dosimetry. In case of electron beam dosimetry, these recommend using parallel-plate ionization chambers beams with R50 values below specific thresholds. However, recent papers suggested cylindrical dosimetry all energies. Here we compared d...

The study of aerosol exposure, dosimetry measurements and related quantitation of health effects are important to the understanding of the consequences of air pollution, and are discussed widely in the scientific literature. During the last 10 years the need to correlate aerosol exposure and biological effects has become especially important due to rapid development of a new, revolutionary indu...

Purpose. This paper describes an advanced system that combines corneal cross-linking with riboflavin with fluorescence dosimetry, the ability to measure riboflavin diffusion within the cornea both before and during UVA treatment. Methods and Results. A corneal cross-linking system utilizing a digital micromirror device (DMD) was assembled and used to measure diffusion coefficients of 0.1% ribof...

Radiation dose is central to much of radiobiological research. Precision and accuracy of dose measurements and reporting of the measurement details should be sufficient to allow the work to be interpreted and repeated and to allow valid comparisons to be made, both in the same laboratory and by other laboratories. Despite this, a careful reading of published manuscripts suggests that measuremen...

Abstract The theranostic concept to use diagnostic and therapeutic nuclides image treat cancer was established many years ago for thyroid disease. With the success of [ 177 Lu]-labeled agents targeting neuroendocrine tumors or prostate cancer, interest this has been significantly rising. possibility localize quantify a target within patient opens up novel possibilities, but also challenges sele...

Rapid and reliable methods for performing biological dosimetry are of paramount importance in the event of a large-scale nuclear event. Traditional dosimetry approaches lack the requisite rapid assessment capability, ease of use, portability and low cost, which are factors needed for triaging a large number of victims. Here we describe the results of experiments in which mice were acutely expos...