The rapid evolution of all sequencing technologies, described by the term Next Generation Sequencing (NGS), have revolutionized metagenomic analysis. They constitute a combination of high-throughput analytical protocols, coupled to delicate measuring techniques, in order to potentially discover, properly assemble and map allelic sequences to the correct genomes, achieving particularly high yiel...

Brucellosis is a well-known infection in domestic animals which caused by Brucella bacterium. Due toserious economic and medical consequences of this disease, various efforts have been made to prevent theinfection through the use of recombinant vaccines based on Brucella outer membrane protein (OMP)antigens. The objectives of the present study were cloning, sequencing and epitope prediction of ...

ipad gene is amongst key genes in shigella invasion, known as an antigen. pa20 protein of bacillus anthracic can be separated from native pa protein during the infection and can be found in the serum of the infected patients and make it possible to diagnose the disease. ctxb, a known immune adjuvant, enhances the immunogenicity and is mainly used for the production of recombinant vaccines as a ...

Life sciences research and development has opened up new challenges and opportunities for bioinformatics. The contribution of bioinformatics advances made possible the mapping of the entire human genome and genomes of many other organisms in just over a decade. These discoveries, along with current efforts to determine gene and protein functions, have improved our ability to understand the root...

esophagus cancer is the eighth most common cancer worldwide and particularly high in an area extending from the southern border of the caspian sea in iran across central asia to china. since information about this mysterious disease is poor, proteomics may be solving this enigma. altering gene expression in cancer cell is a remarkable indicator can be detected by proteomics techniques and bioin...

the aim of this investigation was conducted to proteomic analysis of plasma obtained from pregnant women who destined to develop late-onset preeclampsia without intrauterine growth restriction (iugr) during 16 th week of gestation. plasma was obtained from primiparous women during 16 th week of gestation. 2-de proteomic analysis was done for plasma from 11 healthy pregnant women and 11 women wh...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Complex Systems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Recurrence Quantification Analysis . . . . . . . . . . . . . . . . . . . . . ...