Background and Aims: Uropathogenic Escherichia coli (UPEC) are considered major reservoir for genes encoding antimicrobial resistance. The mechanism of resistance and persistence of UPEC has been attributed to the production of biofilm and Extended Beta Lactamase (ESBL). This hospital-based prospective study determined how biofilm and ESBL production facilitate antibacterial resistance amongst ...

Objective(s): Bacterial biofilm formation causes many persistent and chronic infections. The matrix protects biofilm bacteria from exposure to innate immune defenses and antibiotic treatments. The purpose of this study was to evaluate the biofilm formation of clinical isolates of Pseudomonas aeruginosa and the activity of zinc oxide nanoparticles (ZnO NPs) on biofilm. Materials and Methods: Aft...

the ability of uropathogenic e. coli (upec) to cause symptomatic uti is associated with the expression of a variety of virulence factors. biofilm formation enables upec to resist the flow of urine and increases its tolerance to antimicrobials and the host immune response. the measurement of biofilm formation in vitro is affected by the type of culture medium used. the aim of this study was to e...

conclusions the potential to form biofilm correlated with antibiotic resistance and ampc production in non-burn burn isolates of a. baumannii. on the other hand, the burn strains produced significantly higher amounts of esbl yet biofilm production was unrelated to antibiotic resistance or esbl-production. materials and methods sixty isolates of a. baumannii were employed of which, 30 were burn ...

Background: N-Acyl homoserine lactone (AHL) is found to be the main component of quorum sensing (QS) in Gram-negative bacteria and plays an important role in biofilm formation. Little information is available regarding the role of AHL in biofilm formation in Escherichia coli (E. coli). The purpose of this investigation was to biochemically detect and characterize AHL activity in biofilm-forming...

conclusions adsorption of antibodies to bap might interfere with bacterial adhesion to the surface. these antibodies were found to be potent biofilm inhibitors. results injection of bap subunit resulted in high titers of antibody. immunized mice serum had significant (p< 0.001) inhibitory effect on biofilm formation. in vitro inhibition of biofilm formation by a. baumannii was studied at 1:50 c...

background: acinetobacter baumannii is commonly resistant to nearly all antibiotics due to presence of antibiotic resistance genes and biofilm formation. in this study we determined the presence of certain antibiotic-resistance genes associated with biofilm production and the influence of low iron concentration on expression of the biofilm-associated protein gene (bap) in development of biofilm...

P. aeruginosa has been mentioned as the major causative agents of nosocomial infections. Pseudomonas infections are often serious and show different resistance to treatment due to distribution of antimicrobial resistance. Meanwhile, some strains are also able to form biofilm during contamination, which help bacteria to be even more persisyant to yreatment. We examined the antibiotic resistance ...

background and purpose: in people wearing dentures, the growth of various candida species under the prosthesis leads to the formation of biofilm, which can play the role of a reservoir for candida and other kinds of microbes. since nano-chitosan particles can cause lasting antimicrobial activity, a more recent approach that utilizes acrylic resins with nano-chitosan particles is proposed. there...