OBJECTIVE To explore the application value of injectable bioactive glass in the restoration of the oral bone defect. PATIENTS AND METHODS This study included 58 consecutive patients with oral bone defect > 1 mm, these patients were randomly assigned to a control group (n=26, Hydroxyapatite bioceramics) and an observation group (n=32, Injectable bioactive glass). The purpose of this study was ...

The guided bone regeneration (GBR) procedure has been used successfully when there is insufficient bone volume for implant placement 1-3) . Bone graft materials are used in conjunction with barrier membranes to improve the outcomes of GBR procedures: they stabilize the blood clot, prevent membrane shrinkage and maintain the space available for new bone formation beneath the membrane 4-6) . Auto...

Bioactive glass is used as both a bone filler and as a coating on implants, and has been advocated as a potential osteogenic scaffold for tissue engineering. Rat-derived mesenchymal stem cells (MSCs) show elevated levels of alkaline phosphatase activity when grown on 45S5 bioactive glass as compared to standard tissue culture plastic. Similarly, exposure to the dissolution products of 45S5 elev...

Bioactive and bioresorbable composite materials were fabricated using macroporous poly(DL-lactide) (PDLLA) foams coated with and impregnated by bioactive glass (Bioglass) particles. Stable and homogeneous Bioglass coatings on the surface of PDLLA foams as well as infiltration of Bioglass particles throughout the porous network were achieved using a slurry-dipping technique in conjunction with p...

Bioactive glasses were synthesized in an inexpensive hydrothermal chemical route by the use of microwave energy irradiation. Compositional changes were carried out to synthesis bioactive glass with different Si content. Densification behavior was investigated by microwave sintering process from 700 °C to 1000 °C temperature. The powders were characterized for their physical and morphological ch...

This study investigates the dissolution behavior as well as the surface biomineralization in simulated body fluid (SBF) of a paste composed of glycerol (gly) and a bioactive glass in the system CaO-MgO-SiO₂-Na₂O-P₂O₅-CaF₂ (BG). The synthesis of the bioactive glass in an alumina crucible has been shown to significantly affect its bioactivity due to the incorporation of aluminum (ca. 1.3-1.4 wt %...

In the current study cerium or galliumcontaining silicate based 13-93 bioactive glass powders were prepared using sol-gel method. Cerium and gallium ions were chosen due to their well-known therapeutic actions and antimicrobial properties. Effect of cerium and gallium substitution (up to 5w%) on the in vitro bioactivity, and mechanical properties of the prepared powders and scaffolds were asses...

A solid freeform fabrication technique, freeze extrusion fabrication (FEF), was investigated for the creation of three-dimensional bioactive glass (13-93) scaffolds with pre-designed porosity and pore architecture. An aqueous mixture of bioactive glass particles and polymeric additives with a paste-like consistency was extruded through a narrow nozzle, and deposited layer-by-layer in a cold env...