The effects of different cooking methods on total bioactive compound content were determined, and in vitro antioxidant activity in 80% ethanolic extracts of Brussels sprouts was evaluated by spectrophotometric methods. Compared to uncooked, steamed, and microwaved Brussels sprouts extracted with 80% ethanol contained higher amounts of total polyphenols. Uncooked Brussels sprouts contained the h...

Granulosa cells form ovarian follicles and play important roles in the growth and maturation of oocytes. The protection of granulosa cells from cellular injury caused by oxidative stress is an effective therapy for female infertility. We here investigated an effective bioactive compound derived from Prunus mume seed extract that protects granulosa cells from hydrogen peroxide (H2O2)-induced apo...

*Corresponding author E mail: [email protected] J. Pharm. BioSci. 3(2013) 114-123 Abstract Pyrazole is five membered heterocyclic rings which is versatile lead compound for designing potent bioactive agent. The interesting groups of this compound has diverse biological activities such as antimicrobial, anti-inflammatory, anticancer, analgesic, anticonvulsant, anthelmintic, antioxidant an...

In the title compound, C11H10N2O3, which is a potential bioactive compound, the benzene and oxa-diazole rings are approximately coplanar, with an inter-ring dihedral angle of 4.14 (2)°, while the ester plane is rotated out of the benzene plane [dihedral angle = 82.69 (9)°]. In the crystal, the mol-ecules form layers down the a axis with weak π-π inter-actions between the oxa-diazole and benzene...

Photolysis of Salannin (1), an important bioactive compound from Azadirachta indica A.Juss (Neem), affords ∆-isosalanninolide (2), a hitherto unknown compound, along with isosalanninolide (3) and salanninolide (4). A probable mechanism has been suggested. While the mechanism of formation of 2 involves both a [4+2] cycloaddition and a [1,3] sigmatropic shift in the furan and D-rings, respectivel...

Postharvest processing affects the chemical components and sensory attributes of coffee beans. This study aimed to evaluate effect postharvest on caffeoylquinic acids alkaloids (bioactive compounds) (aroma taste) brewed coffee. Coffee beans Kalosi-Enrekang were processed using three methods (honey, natural, full-washed), roasted at a medium degree, with tubruk brewing techniques. Bioactive comp...

In recent years, researchers hunt for a novel anticancer agent mainly from plants. Phytochemicals and ubiquitous bioactive compound plays an important role in drug development. Among various phytochemicals, polyphenols have attracted considerable interest in the past few years due to their potential health benefits. One such phytochemical namely Coumarin (1,2-benzopyrone), a phenolic compound d...