نتایج جستجو برای: binding protein 1
تعداد نتایج: 3783233 فیلتر نتایج به سال:
Background: Denileukin diftitox (trade name, Ontak) is the first recombinant immunotoxin (IM), in which the binding domain of diphtheria toxin has been replaced by the amino acid sequence of human interleukin-2 (DT389IL-2) using genetic engineering. Purity, stability, and structural property of the protein are critical factors for the scale-up production of this fusion protein. In this IM, loca...
Deoxyribonucleic acid (DNA) is an important molecular target for anti-cancer agents due to its involvement in gene expression and protein synthesis which are fundamental steps in cell division and growth. A number of antineoplastic agents interfere with DNA and hence disturb the cell cycle. Compounds including planar aromatic rings are privileged scaffolds in binding to the DNA. This characteri...
background and objectives: streptococcus pneumoniae, a major human pathogen, is closely related to the commensal species s. mitis and s. oralis. s. pneumoniae surface proteins are implicated in virulence and host interaction of this species, but many of them have recently been detected in s. mitis b6 in silico. we tested for the presence of such genes usinga set of eight s. mitis and eleven s. ...
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