Total tissue content and molecular mass of hyaluronic acid was determined in papain digests of human articular cartilage using a sensitive radiosorbent assay [Laurent & Tengblad (1980) Anal. Biochem. 109, 386-394]. 1) Hyaluronic acid content increased from 0.5 microgram/mg wet wt. to 2.5 micrograms/mg wet wt. between the ages of 2.5 years and 86 years. 2) Hyaluronic acid chain size decreased fr...

BACKGROUND Although the safety profile of hyaluronic acid fillers is favorable, adverse reactions can occur. Clinicians and patients can benefit from ongoing guidance on adverse reactions to hyaluronic acid fillers and their management. METHODS A multinational, multidisciplinary group of experts in cosmetic medicine convened the Global Aesthetics Consensus Group to review the properties and c...

Acute pseudoseptic arthritis is a very rare complication that is associated with intra-articular hyaluronic acid injections, which normally involve minimal risk. The most common adverse events that are caused by hyaluronic acid injections are inflammatory reactions or flares at the injection site. In this study, we described three cases of acute pseudoseptic arthritis that was caused by hyaluro...

CD44 is a polymorphic glycoprotein expressed on the surface of many tissues and cell lines which has been implicated in a number of cellular functions including lymphocyte homing to mucosal lymphoid tissue (Peyers patches), leukocyte activation, lymphopoiesis, and tumor metastasis. The predominant isoform found on human leukocytes, CD44H, is a receptor for hyaluronic acid. Because of the promin...

Objective To evaluate the efficacy of intra-articular viscosupplementation therapy with hyaluronic acid for pain relief of knee osteoarthritis, we conducted a meta-analysis of randomized, doubleblinded, placebo-controlled trials. Methods We searched systematically for randomized, double-blinded, placebo-controlled trials of hyaluronic acid (hyaluronan and hylan G-F20) for pain relief of knee os...

All major glycosaminoglycans except keratan sulphate are found in animal lung and pleura (Wusteman, 1972). Pleural fluids from patients with several pulmonary diseases contain mostly hyaluronic acid (Friman, Hellstrom, Juvani & Riska, 1977). The high concentration of hyaluronic acid in pleural fluid associated with mesothelioma is considered diagnostic of this disease (Havez, Degand, Boersma & ...

A readily available source of pure hyaluronic acid is a necessity in studies involving the ground substance of connective tissue and its relation to diverse spreading factors thought to be important in the pathogenesis of many bacterial diseases. Any objection that contamination with other mucopolysaccharides or protein of hyaluronic acid prepared from mammalian sources is generally likely, unl...

Although endovascular stenting has been used as an interventional therapy to treat cardio- and cerebro-vascular diseases, it is associated with recurrent vascular diseases following stent thrombosis and in-stent restenosis. In this study, a metallic stent was coated with dopamine-conjugated hyaluronic acid with different ratios of catechol group to improve hemocompatibility and re-endothelializ...

In this paper, −10 μm rutile and −30 garnet particles were selected as samples. The effects of different reagents on the flotation single minerals studied, mechanism was analyzed by contact angle, zeta potential, Fourier transform infrared (FTIR) measurements. results show that an optimal recovery is obtained with benzohydroxamic acid (BHA) collector for sodium silicofluoride (SSF) inhibitor ga...