Lower urinary tract symptoms (LUTS) are a common complaint among aging men and are often caused by benign prostatic hyperplasia (BPH). A number of medical treatments for LUTS/BPH exist, such as alpha-blockers, 5alpha-reductase inhibitors, anticholinergics, phosphodiesterase type 5 (PDE5) inhibitors, and combination therapies. Agonist binding of the alpha(1A)-adrenergic receptor (AR), causing pr...

Testosterone replacement therapy (TRT) represents an increasing popular treatment option for men with late-onset hypogonadism (LOH). Because of unsubstantiated beliefs of testosterone's effect on the prostate, the FDA has recently placed a warning on testosterone products, stating that TRT may worsen benign prostatic hyperplasia (BPH). Within this review article we have demonstrated the current...

EDITORIAL article Front. Urol., 30 December 2022Sec. Male Urology Volume 2 - 2022 | https://doi.org/10.3389/fruro.2022.1115743

BACKGROUND: Clinical prostatic diseases occur in 80% of dogs over 5 and 95% over 9 years of age. . It seems that benign prostatic hyperplasia) BPH) affect Scottish terriers more severely than the other breeds. OBJECTIVES: This study aimed to evaluate the changes of biochemical and hematological parameters in BPH dogs. METHODS: Blood samples were collected from 10 male dogs older than five year...

Background: We evaluated the efficacy and tolerability of tamsulosin versus terazosin in patients with signs and symptoms of benign prostatic hyperplasia (BPH). Methods: Patients (N = 1,993) were randomized to tamsulosin (0.4 mg/day) or terazosin (5 mg/day, following titration). The primary efficacy endpoint was total American Urological Association Symptom Index (AUA-SI) score after 4 days of ...

Despite the high incidence of benign prostatic hyperplasia (BPH), so far a conservative treatment modality has not been established internationally (4,5). The reasons for this are the multifactorial etiology of the symptoms in patients with BPH (5) and the lack of suitable animal models to elucidate the pathogenesis of BPH (5,9). This makes the search for conservative therapies aimed at the und...

Benign Prostatic Hyperplasia (BPH) a noncancerous enlargement or hypertrophy of the prostate, is one most common diseases in aging men. It can cause bothersome lower urinary tract symptoms that affect quality life by interfering with normal daily activities and sleep patterns. A Descriptive study was conducted to identify risk elderly adults prostatic symptoms. total 50 selected purposive sampl...